Block 2

Question 1

What does “M” stand for?

Answer 1

Mix

Question 2

What does Ft stand for

Answer 2

make

Question 3

BUD for non-H2O non-sterile compounded products?

Answer 3

6 months

Question 4

BUD for non-oral, aqueous non-sterile compounded products?

Answer 4

30 days

Question 5

BUD for oral, aqueous non-sterile compounded products?

Answer 5

14 days

Question 6

What must be included in the labeling of non-sterile compounded product?

Answer 6

1) notification of a compounded product

2) BUD & storage

Question 7

What should be included in the education materials upon dispensing of a non-sterile compounded product?

Answer 7

1) OBRA 90 Requirements
2) storage/handling/disposal
3) ADR reporting
4) changes in physical characteristics

Question 8

What are glass mortars used for?

Answer 8

1) staining / potent drugs

2) preferred for liquids / semi-solids

Question 9

What are the considerations for use of a glass mortar?

Answer 9

1) no emulsions

2) nothing hard – no glass spatula!

Question 10

What is a wedgewood mortar used for?

Answer 10

1) emulsions

2) grinding or crystals / large particles

Question 11

What are the considerations for use of a wedgewood mortar?

Answer 11

1) it is porous – no staining or potent drugs

Question 12

What is a porcelain mortar used for?

Answer 12

Same as wedgewood, but less expensive.

1) emulsions
2) grinding or crystals / large particles

Question 13

What are considerations for use of a porcelain mortar?

Answer 13

1) it is porous – no staining or potent drugs

2) less durable than wedgewood

Question 14

Methods for comminution?

Answer 14

1) pulverization by intervention
2) eutectic mixtures
3) levigation
4) trituration

Question 15

What does comminution mean?

Answer 15

reduction of particle size

Question 16

What are the methods of blending?

Answer 16

1) spatulation
2) trituration
3) tumbling

Question 17

How is levigation different from spatulation?

Answer 17

Grinding in levigation gets particle size reduction.

Question 18

Describe trituration.

Answer 18

a circular motion in the mortar & pestle achieving particle size reduction by outward & inward circles. Powders are removed from side of mortar with rubber spatula

Question 19

Describe levigation

Answer 19

A mass of solid is formed by addition of minimal liquid. Grinding. In pestle or on ointment slab

Question 20

Describe spatulation.

Answer 20

Move spatula through powders on an ointment slab or in mortar;; no particle size reduction is achieved

Question 21

What are the considerations for adding a drug to formulary?

Answer 21

1) indication & clincal utility
2) dosing interval
3) mechanism of action
4) dosage forms
5) ADRs, C/Is
6) Age restriction
7) Cost