UroPathogenic E.coli (UPEC) Flashcards
1
Q
what is the biology of UPEC?
A
- Gram Negative Bacilli
- Lactose Fermenter
- Reduce Nitrate to Nitrite
2
Q
how is the course of the pathogenesis of UPEC?
A
Fimbriae attaches to uro-epithelial cells and biofilm is formed.
3
Q
what will cause the Pyogenic symptoms seen in UPEC?
A
are mediated by hemolysin and immune response to LPS
4
Q
where is UPEC flora normal in the body?
A
colon
5
Q
how is UPEC infection get acquired in hospitals?
A
through catheters
6
Q
how is UPEC infection get acquired in the community?
A
lack of hygiene
7
Q
how will an infection with UPEC present with?
A
- UTI/Cystitis (90% of cases)
- Low grade fever, dysuria
- Pyelonephritis
- high fever, dysuria, low flank pain
8
Q
how is an infection with UPEC diagnosed?
A
Urinalysis
9
Q
how do you treat UPEC?
A
*TMP-SMX
*Fluoroquinolones
\*Based on urinalysis Ab-R/S
10
Q
what will a UTI Urinalysis detect?
A
Nitrites
11
Q
A
