Clinical 6.2 Microbiology of acute diarrhoea Flashcards

1
Q

What are the indications for a stool sample?

A

Returned travellers, hospitalised patients, bloody stools, systemic toxicity, recent antibiotic use and persisting beyond 4-5 days

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2
Q

What are the 3 bacteria on MCS?

A

Campylobacter jajuni, Salmonella and Shigella

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3
Q

What is the collection process for fecal samples?

A

avoid contamination with water or urine

3 specimens over 5-7 days and deliver as soon as possible

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4
Q

What should you test for when there is a history of recent antibiotic use/hospitalisation?

A

C.difficile

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5
Q

What should you test for when there is severe watery diarrhoea with recent overseas travel?

A

Vibrio cholera

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6
Q

What should you test for when there is a history of consumption of uncooked seafood ?

A

Vibrio parahaemolyticus

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7
Q

What should you test for with abdominal pain and pseudoappendicitis?

A

Yerseinia enterocolitica

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8
Q

What should you test for with bloody diarrhoea following fatty food followed by renal failure and haemolysis?

A

EHEC or shiga toxin producing E.coli

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9
Q

What should you test for with an outbreak of vomiting and non-inflammatory diarrhoea in hospital or nursing home?

A

Norovirus

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10
Q

what should you consider in non-inflammatory diarrhoea in children?

A

Rotavirus or Adenovirus

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11
Q

What type of diarrhoea is associetd with a swimming pool?

A

Clostridium

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12
Q

Foul smelling fatty diarrhoea

A

Giardia

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13
Q

What should you consider with severe bloody diarrhoea after overseas travel?

A

Entamoeba histolytica

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14
Q

How do you test for C.difficile?

A

Rapid antigen testing
ELISA
Nucleic acid amplification
Cytotoxic testing

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15
Q

What causes vibrio cholera intoxication

A

Fresh water

Shellfish

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16
Q

Do you get fever with virbio cholera?

A

No

17
Q

Which pathogens should you not give antibitoics for?

A

EHEC and shiga-toxin producing E.coli

18
Q

What is the most common cause of non-bacterial diarrhoea?

A

Norovirus

19
Q

What are the bacterial causes of acute diarrhoea?

A
Campylobacter jejuni 
Salmonella 
Shigella 
E.Coli 
C.Difficile
20
Q

What are the viral causes of acute diarrhoea?

A

Rotavirus
Norovirus
Enteric adenovirus

21
Q

What are the parasitic causes of acute diarrhoea?

A

Giardia

Cryptosporidium

22
Q

How do you distinguish between E.Coli strains?

A

Nucleic acid based tests

23
Q

What are the features of viral diarrhoea?

A
afebrile low grade fever 
Vomiting prominent 
Pale, large volume stool 
Absence of food 
Self limited 
NO specific treatment