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36. Cancer chemotherapy III (Topoisomerase inhibitors. Inhibitors of mitotic spindle) Flashcards

(6 cards)

1
Q

Which are the groups of drugs?

A
  • Topoisomerase I inhibitors:
    • Topoisomerase I inhibitors (Camptothecins)
    • Topoisomerase II inhibitors
      • Anthracyclines
      • Anthracenediones
      • Epidophyllotoxins
  • Inhibitors of mitotic spindle:
    • Taxane derivatives
    • Vinca alkaloids
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2
Q

Which are the topoisomerase I inhibitors?

A

Camptothecins:

  • Irinotecan
  • Topotecan
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3
Q

Which are the topoisomerase II inhibitors?

A
  • Anthracyclines:
    • Doxorubicin
    • Epirubicin
    • Daunorubicin
    • Idarubicin
  • Anthracenediones:
    • Mitoxantron
  • Epidophyllotoxins:
    • Etoposide
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4
Q

Which are the taxane derivatives of the inhibitors of the mitotic spindle?

A
  • Paclitaxel
  • Docetaxel
  • Cabazitaxel
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5
Q

Which are the vinca alkaloids inhibitors of the mitotic spindle?

A
  • ​Vincristine
  • Vinblastine
  • Vinorebline
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6
Q

Which are the other inhibitors of the mitotic spindle?

A

Estramustin phosphate

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