Physiology Flashcards
What is the rate of glomerular filtration
125ml/min
180l/day
What do the kidneys reabsorb
99 percent fluid 99 percent of salt all glucose all amino acids half of urea no creatinine
What is reabsorbed in the proximal tubule
sugars amino acids phosphate sulphate lactate
What is secreted in the proximal tubule
hydrogen hippurates neurotransmitters bile uric acid drugs toxins
What is primary active transport
energy is directly required to operate the carrier and move the substrate against its concentration gradient
what is secondary active transport
the carrier molecule is transported coupled to the concentration gradient of an ion
What is facililtate diffusion
passive carrier mediated transport of a substance down its concentration gradietn
What is needed to reabsorb sodium at the basolateral membrane of the tubular cell
Na+K-ATPase channcel
What is the renal threshold of plasma glucose befor it can no longer continue to reabsorb it and it will be excreted
10-12mmol/l
Where are all glucose and amino acids reabsorbed
the proximal tubule
what is the fluid leaving the proximal tubule like
iso osmotic
What is reabsorbed in the ascending limb
sodium and chlorine reabsorbed
(achieved by active transport in the thick AL and by passive transport in the thin AL
What are the features of the descending limb
does not reabsorb salt and is highly permeable to water
How is salt reabsorbe in the ascending limb
triple co transporter
What blocks the triple co transporter
loop diuretics
