COPD Flashcards

1
Q

Difference between

  • COPD
  • Emphysema
  • Chronic bronchitis
A
  • COPD - a lung disease
    • Progressive and irreversible lung disease characterised by persistent airflow limitation

gas trapping and an enhanced chronic inflammatory response.

  • Emphysema - a description of lung changes
    • Destruction of alveolar walls
    • Narrowing of small airways
  • Chronic bronchitis - a description of symptoms
    • Chronic productive cough >3 months a year for >2 years
    • Can occur before COPD develops
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2
Q

Risk factors for developing COPD (4)

A
  1. Smoking
  2. Air pollutants (poorly vented cooking, heating fires)
  3. Occupational exposure (coal miners, gold miners, welders, silica)
  4. Family history (alpha 1-antitrypsin deficiency)
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3
Q

Precipitants of COPD exacerbations (4)

A
  1. Infection
  2. Environmental irritants
  3. Cold weather
  4. PE
  5. Change to management
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4
Q

Symptoms of COPD (2)

A
  1. Dyspnoea
  2. Chronic productive cough
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5
Q

Signs of COPD on auscultation (2)

A
  1. Decreased air entry
  2. Wheeze
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6
Q

GOLD grading of COPD severity on spirometry

A
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7
Q

Signs of COPD on CXR (4)

A
  1. Overexpanded lungs
  2. Flattened diaphragm
  3. Increased retrosternal space
  4. Bullae
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8
Q

ABCD assessment of COPD severity

A
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9
Q

Lifestyle management of COPD (4)

A
  1. Smoking cessation
  2. Physical activity
  3. Flu vaccine, pneumococcal vaccine
  4. Pulmonary rehabilitation
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10
Q

Pharmacological management of COPD (according to ABCD severity groups)

A
  • SABA - salbutamol, terbutaline
  • SAMA - ipratropium
  • LABA - salmeterol, eformeterol
  • LAMA - tiotrpium
  • ICS - fluticasone, budesonide
  • Oral corticosteroids - treat and prevent acute exacerbations, no mortality benefit when used alone
  • Theophylline - consider at any stage, beware of harms
  • Antibiotics (macrolide) - prevent exacerbations
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11
Q

Complications of COPD (2)

A
  • Right heart strain (cor pulmonale)
  • Vigorous coughing → rib fractures, syncope
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