3.8) Fundamental Pharmaceutics

Question 1

Medicines are

Answer 1

API delivery systems

Question 2

What is form of medicine

Answer 2

its the means of administering APIs to the body safely, efficiently, reproductively, reproducibly and convenienty

Question 3

Define pharmaceutics according to Aulton’s Pharmaceutics

Answer 3

process of converting an API into a medicine

Question 4

Pharmaceutics is concerned with

Answer 4

science and technological aspects of designing and manufacturing dosage forms

Question 5

Pharmaceutics involves

Answer 5

-Physical pharmaceutics
-biopharmaceutics
-dosage form design
-compounding and pharmaceutical technology
-pharmaceutical microbiology

Question 6

Define physical pharmaceutics

Answer 6

an understanding of fundamental physical chemistry is necessary for efficient design of dosage forms

Question 7

Define niopharmaceutics

Answer 7

an understanding of relevant body systems and how APIs arrive there following admin

Question 8

Define dosage form design

Answer 8

design and formulation of medicines

Question 9

Define compounding

Answer 9

maunfacture of these medicines on small scale

Question 10

Define pharmaceutical technology

Answer 10

manufacture of these medicines on large scale

Question 11

Define Pharmaceutical microbiology

Answer 11

avoidance and elimination of microorganisms in medicines

Question 12

Name the 3 major consideration in dosage design forms

Answer 12

1. physicochemical properties of APIs
2. biopharmaceutical considerations
3. therapeutic considerations

Question 13

Egs of biopharmaceutical considerations

Answer 13

-how admin route of a dosage form affects the rate and extend of API absorption into the body

Question 14

Therapeutic considerations of the diseases decide

Answer 14

-most suitable dosage form
-possible routes of admin
-most suitable DOA
-dose frequency for the API in question

Question 15

What needs to be taken into account when identifying admin routes

Answer 15

-physical and chemical properties of both API as well as additiives need to be understood
-factors influencing APIs absorption
-requirements of disease to be treated

Question 16

What is required to formulate an API

Answer 16

interpretation and application of a wide range of info from several study areas

Question 17

What must be done to creat high-quality, safe and efficacious dosage forms

Answer 17

careful examination
analysis
evaluation of wide ranging info