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Oral Histology > Odontogenesis > Flashcards

Odontogenesis Flashcards

1
Q

From what type of cells do tooth tissues derive from?

A

Stem cells originating in the ectoderm primary germ layer

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2
Q

When does odontogenesis occur?

A

6th embryonic week

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3
Q

What two tissues from the ectoderm are involved in odontogenesis?

A

Epithelium and mesenchyme

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4
Q

Dentinogenesis

A

Formation of dentin

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5
Q

Amelogenesis

A

Formation of enamel

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6
Q

Cemetogenesis

A

Formation fo cementum

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7
Q

What are the epithelial stages based on

A

Histological shapes of the epithelial tissue within a mesenchymal environment

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8
Q

What are the epithelial stages of tooth development?

A

Epithelial dental lamina stage
Epithelial bud stage
Epithelial cap stage
Epithelial bell stage

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9
Q

At what stage is the epithelium is arranged in 4 distinct cell layers

A

Epithelial bell stage

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10
Q

What happens during the tooth germ stage

A

Odontogenic epithelial and mesenchymal tissues are combined

Cells of each tissue is induced specifically to become fomative cells of dentin, enamel, cementum, and pulpal tissues

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11
Q

What tissue does the enamel organ derive from?

A

Epithelium

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12
Q

What tissue does the dental papilla drive from?

A

Mesenchyme

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13
Q

What tissue does the dental follicle derive from?

A

Mesenchyme

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14
Q

What occur during the primary dental lamina stage

A

Two epithelial invaginations appear in the lower anterior region of the lower jaw and later in the same week (6th) in the upper jaw
The invaginations descend into the underlying mesenchymal tissue (ectomesenchyme) and continue posteriorly within the mesenchyme as continuous epithelial bands

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15
Q

What are the 2 invaginations of the primary dental lamina stages?

A

Vestibular lamina

Primary dental lamina

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16
Q

Vestibular lamina

A

Facial band of invagination during primary dental lamina stage
Cell death will occur in the center of the vestibular lamina, leaving space known as the ‘vestibule’

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17
Q

Primary dental lamina

A

Lingual band of invagiation during primary dental lamina stage
Cells arising form the dental laminae (primary and secondary) become odontogenic epithelial part of tooth germ

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18
Q

Epithelial bud stage

A

Cells at the deep end of the dental lamina develop into epithelial knobs, known as ‘epithelial bud’
Each bud is surrounded by mesenchymal tissue, and bud cells are continuous with cells of the primary dental lamina

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19
Q

When do primary buds form?

A

6-8 weeks in utero

20
Q

When do permanent buds form?

A

4 months in utero to 5 years postnatal

21
Q

When do primary central incisor buds form?

A

6 weeks in utero

22
Q

When do primary second molar buds form?

A

8 weeks in utero

23
Q

When do first molar permanent buds form?

A

4 months in utero

24
Q

When do permanent central incisor buds form?

A

5 months in utero

25
Q

When do permanent second molar buds form?

A

10 months postnatally

26
Q

When do permanent third molar buds form?

A

5 years postnatally

27
Q

Epithelial cap stage

A

Odontogenic epithelial is in the shape of the cap

-this cap used to be the epithelial bud

28
Q

Enamel knot

A

Concentration of epithelial cells in the epithelial cap

Signaling center to determine if the tooth will develop to become an anterior or posterior tooth

29
Q

Epithelial bell stage

A

Epithelial cap undergoes growth and develops into a bell shaped epithelial structure called the ‘enamel organ’
Epithelium is in 4 distinct layers

30
Q

What are the 4 cell layers of the epithelial bud stage?

A

Inner epithelial layer
Stratum intermedium epithelial layer
Stellate reticulum epithelial layer
Outer epithelial layer

31
Q

What layer of the epithelial bell becomes the ameloblasts?

A

Inner epithelial layer

32
Q

Secondary dental lamina

A

Lingual to the primary tooth germ

Arises from the primary dental lamina - not the oral epithelium

33
Q

How many secondary lamina arise in each arch?

A

10 - one for each secondary tooth

34
Q

Tooth germ stage

A

The epithelial enamel organ and a closely associated ectomesenchymal tissue that is continuous form around the epithelium to within the epithelium
-when combined, the enamel organa and ectomesenchyme are a tooth germ

35
Q

What are the 3 parts of the tooth germ?

A

Enamel organ
Dental papilla
Dental follicle

36
Q

Enamel organ

A

Avascular tissue from epithelium

inner epithlial cells differentiate into ameloblasts

37
Q

After formation of the enamel is complete, ameloblasts, along with the other layers of the enamel organ come together to form what?

A

Reduced enamel epithelium

38
Q

What is the purpose of the reduced enamel epthelium?

A

It is a protective structure over the surface of the enamel until the tooth enters the oral cavity

39
Q

Dental papilla

A

Vascular tissue form mesenchyme
Stem cells become odontoblasts, fibroblasts, and reserve cells
Ultimately becomes the pulp of the tooth

40
Q

Dental follicle

A

Vascular tissue from mesenchyme
Stem cells become cementoblasts, fibroblasts, osteoblasts, and reserve cells
Ultimately becomes the periodontal ligament of the periodontium

41
Q

Where is the initial site of appearance of ameloblasts and odontoblasts?

A

Within the tooth germ along the area between the papilla and the inner cells of the enamel organ

42
Q

Ameloblasts form what?

A

Enamel

43
Q

Odontobalsts form what?

A

Dentin

44
Q

What is the fate of enamel organ cells after completion of enamel?

A

The 4 cell layer come together to form the reduced enamel epithelium

45
Q

Cervical loop

A

Rim of the epithelial bell

This is the site where the inner and outer cells merge

46
Q

Fate of the cervical loop

A

Outer and inner layers come together to form a double epithelial layer called ‘Hertwig’s epithelial root sheath’

47
Q

Hertwig’s epitheliual root sheath

A

Determines the root-dentin outline

Determines the number of root canals of the tooth

Oral Histology (12 decks)

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