Quiz 4 Flashcards

1
Q

Osteoarthritis – findings on plain film:

A
  • joint space narrowing (indicating a loss of articular cartilage)
  • marginal osteophyte formation,
  • subchondral bone cysts
  • sclerosis
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2
Q

Most sensistive marker for RA:

A

Anti-citrullinated protein antibodies – specificity ~95% bc rarely + if RA not present

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3
Q

What joint is the first to be affected by Gout?

A

classic joint of involvement in gout is the 1st MTP joint.

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4
Q

What type of crystals are seen in Pseudogout?

A

calcium pyrophosphate crystals CPPD

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5
Q

What protein is decreased in Duchenne’s Muscular Dystrophy

A

dystrophin

Duchenne’s = MC Muscular Dystrophy

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6
Q

What condition is associated with Thymic abnormalities?

A

Myasthenia gravis

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7
Q

In what condition is acetyl-choline release inhibited at the presynaptic calcium channel

A

Lambert-Eaton syndrome

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8
Q

Hist of Dermatomyositis

A

mixed B and T cells and perifascicular muscle fiber atrophy

- perivascular inflammatory infiltrate

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9
Q

In what condition do we see the appearance of vacuoles in the muscle, deposits of amyloid-related proteins within the muscle cells and inclusions?

A

Inclusion body myositis

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10
Q

MC malignancy soft tissue tumor in children

A

Rhabdomyosarcoma

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11
Q

HIST: -Mosaic pattern of lamellar bone which is likened in appearance to a jigsaw puzzle

A

Paget’s disease

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12
Q

Name for hypermineralization

A

Osteopetrosis: a rare inherited disorder whereby the bones harden and become more dense.

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13
Q

MC organism in Osteomyelitis

A

Staph Aureus

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14
Q

XRAY for Aneurysmal bone cyst

A

honey-combed appearance on xray

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15
Q

Solitary Bone Cyst:

A

symmetrical in its appearance

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16
Q

Characteristic cherry red tissue, surrounded by dense sclerotic bone

A

Osteoid osteoma

17
Q

In what condition do we see skip lesions

A

Osteosarcoma

18
Q

Fibrosarcoma HIST

A

spindle shaped

19
Q

HIST: small, rounded cells, uniform, densely packed

A

Ewing Sacroma