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Erwin Personal Patho Flashcards > Environmental And Nutritional Pathology > Flashcards

Environmental And Nutritional Pathology Flashcards

1
Q

Lead poisoning serum level with decreased IQ

A

10ug/mL

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2
Q

Presents with microcytic hypochromic anemia

A

IdA
Thalassemia
Lead poisoning

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3
Q

Lead poisoning level with frank anemia, nephorpathy, colic and encephalopathy

A

100ug/mL

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4
Q

Level of Lead poisoning that causes death

A

150 ug/mL

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5
Q

Poisoning that causes peripheral demyelinating neuropathy in adults.

Results in wristdrop and footdrop

A

Lead

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6
Q

Impaired uric acid secretion in lead poisoning. PCT with lead inclusions

A

Saturnine gout

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7
Q

Drug of choice for acute management of lead poisoning

A

EDTA +/- Dimercaprol

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8
Q

Drug of choice for outpatient management of lead poisoning

A

Succimer

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9
Q

Sources of mercury poisoning

A

Contaminated fish
Dental amalgam

Mercury vapors
Gold mining

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10
Q

Mercury poisoning that manifest with cerebral palsy, deafness, blindness, and metal retardation

A

Minamata disease (methylmercury)

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11
Q

The main protective mechanism against mercury poisoning

A

Intracellular glutathione

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12
Q

Milk and roses complexion and hyperkeratosis

A

Arsenic poisoning

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13
Q

Transverse bands in nails found in arsenic poisoning

A

Mee’s lines

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14
Q

Associated malignancies of arsenic poisoning

A

SCCA skin
Liver angiosarcoma
Lung cancer

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15
Q

Most common exogenous cause of human cancers

A

Tobacco

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16
Q

Most preventable cause of human death

A

Tobacco

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17
Q

Carcinogens in tobacco

A

Tar
Polycyclic aromatic hydrocarbons
Benzopyrene
Nitrosamine

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18
Q

Metabolizes alcohol to acetyldehyde

A

Acetaldehyde dehydrogenase

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19
Q

Participates in metabolism of high levels of alcohol

A

Microsomal ethanol-oxidizing system (MEOS)

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20
Q

Sharp margins with severed bridging blood vessels

A

Incision

21
Q

Jagged tear with intact bridging blood vessels

A

Laceration

22
Q

Burns confined to the epidermis

A

Superficial

23
Q

Burns that involve injury to the dermis

Pink mottled and painful, with coagulative necrosis

A

Partial-thickness burns

24
Q

Burns that extend to the subcutaneous tissue, may also damage the muscle tissue

White charred dry and painless

A

Full-thickness burns

25
Q

Most common hyperthermic syndrome, sudden inset collapse and prostration d/t failure of cardiovascular compensation to hypovolemia

A

Heat exhaustion

26
Q

Nitrosylation of ryanodine receptor type 1 that leads to hyperthmia and muscle contractors in response to exposure to common anesthetics

A

Malignant hyperthermia

27
Q

Drugs implicated in malignant hyperthermia

A

Halothane

Succinylcholine

28
Q

Drug of choice in treating malignant hyperthermia

A

Dantrolene

29
Q

Action of AC type electrical injury

A

Tetanic contractions (more dangerous)

30
Q

Most radiosensitive tissue

A

Lymphoid tissue

Bone marrow
Mucosa of GI tract
Germinal tissue

31
Q

Least radiosensitive tissues

A

Bone
Brain
Muscle
Skin

32
Q

Hallmark of radiation injury

A

Fibrosis and vascular changes

33
Q

BMI considered malnourished

A
34
Q

deficiency of all nutrients, extremities are emaciated, normal serum albumin

A

Marasmus

35
Q

Hallmark of marasmus

A

Emaciated extremities

36
Q

Most common form of protein-energy malnutrition

A

Kwashiorkor

37
Q

Associated with sever loss of visceral protein, with generealized or dependent edema

A

Kwashiorkor

38
Q

Enlarged fatty liver in kwashiorkor is due to

A

Apolipoprotein B-100 deficiency

39
Q

Small bowel changes in kwashiorkor

A

Mucosal atrophy

Loss of villi and microvilli

40
Q

Has the highest death rate of any psychiatric disorder

A

Anorexia nervosa

41
Q

Calluses on back of the hands from repeated trauma from the incisors seen in bulimia nervosa

A

Russel’s sign

42
Q

Manifestation of Vitamin A deficiency

A

Nyctalopia
Xerophthalmia
Bitot spots
Keratomalacia

Squamous metaplasia
Renal calculi
Total blindness

43
Q

Effects of vitamin A toxicity

A 
Papilledema
Pseudomotor cerebri
Seizures
Hepatitis
Bone pains
44
Q

Vitamin D deficiency

A

Genu varum
Craniotabes
Rachitic rosary
Pigeon breast deformity

45
Q

Vitamin C deficiency

A

Scurvy

Bleeding gums
Loosened teeth
Poor wound healing

Perifollicular hemorrhage

46
Q

Selenium deficiency

A

Cardiomayopqthy (keshan disease)

47
Q

Zinc deficiency

A

Acrodermatitis enteropathica

48
Q

Cherry red color of the skin and mucous membranes

A

Acute carbon monoxide poisoning

Erwin Personal Patho Flashcards (9 decks)

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