4 Flashcards
(20 cards)
to find the overall net charge
add up net charge of all ionizable group
analyze ionizable group’s charge when de & protonated
%xcharge
to find net charge of 1 group
- Henderson Haselbach method
- deproto A- will always be on top bcs A-/HA ‘
- take % X charge or (de)proto / total (A- + HA)
inverse of log
10 ^log
describe the diagram
lower pK, more deproto => stronger acid
higher pK, more proto
NH3+
deprotonated, neutral 0
promotnated, +1 charge
same with NH+ OR NH2+
what is an amino acid
central a-carbon, R group, alpha amino and alpha carboxyl
4 classes of ama
polar: - + uncharged and nonpolar
the lower the pH the lower the concentration of H ions. T or F
F.
nonpolar: list all am.a, 1, 3
GLAciers in ALA VALIantly Locate/ LEUcate Isolated/ILElated PROwlers
Glycine - Alanine - Valine - Leucine - Isoleucine - Proline
1: first letter Z
ISOLEUCINE STRCUTRE
(am.ao CH- methyl (side) (down) C C
proline structure
only 1 w/ ring structure
imino acid
can be hydroxylated
H
NH2+ – C – COOH
C C C
describe polar (-)
ASPartic acid and GLUtamic acid: D & E respectively
carboxlyic acid
what is a carboxylic acid
O = C -OH
Valine (3 -1- structure)
VALI
V
CH w/ /2 methyls
Leucine (3-1-structure)
LEU
L
CH2- valine
describe polar positive
HIS Lost Kid Always Return
HIS/LYS/ARG
H L-K A-R
structure of polar positive
Histidine: C w/ a pentose ring N NH+
lYSINE 4C NH3+
Arg: C C C NH
C– NH2 – NH2+
it covers NH+ NH3+ NH2+
COMPARE methionine vs cysteine
METhodically Check the SULFUR
methionine vs cysteine
np vs polar uncharged
MET vs CYS (M C)
CCSC vs C–SH
in the nonpolar mnemonic wha tis the ionizable
proline, NH2+
TYRosine, OH
Cysteine, SH
explain Aroma of Fine PINE & Yellow Timber is Worth the TRP
PHE (F) vs TYR (Y) vs TRP (W)
alanine + aromatic ring vs only polar unchargede PHE with OH ionizable vs dpentose NH and aromtic
