4-2-1 Endocrine

Question 0

How do u screen for hyperprolactinemia

Answer 0

3 specimens/ 20-30min interval/ average

Question 1

Responsible for the initiation and maintenance of lactation

Answer 1

Prolactin

Question 2

A female has a prolactin leven of 25.5ug?

Answer 2

Hyper!

Question 3

Prolactin ia highest at people when?

Answer 3

Post puberty females

Question 4

HyperProlac situations 4

Answer 4

Pregnancy
Breastfeeding
Prolactinoma
Hypothy

Question 5

By 3rd trimester what level of PRL

Answer 5

500ng

Question 6

PRL >200; acromegaly

Answer 6

Pituitary adenoma

Question 7

PRL inhibits what hormone?

Answer 7

GnRH

Question 8

Inhibits GH release

Answer 8

Somatostatins

Question 9

Negatively feeds back on pituitary to inhibit gh releas

Answer 9

Igf1

Question 10

Scretory peak of GH

Answer 10

20-40ng

Question 11

Dx of gh deficiency

Answer 11

Gh measurement upon pharma stimulation

Question 12

Meant by: failure of GH suppression after oral glucose load

Answer 12

Gh xs

Question 13

2 causes of GH deficiency

Answer 13

Idiopathic

Pituitary adenoma

Question 14

Gold std for Dx of GHD

Answer 14

Insulin tolerance test

Question 15

Pediatric px GH is measured in ITT as 9ng? Normal or deficient?

Answer 15

Deficient
Normal >10ng
Adult >5ng

Question 16

Second confirmatory test for GHD

Answer 16

Arginine combo GHRH test

Question 17

Growth hormone excess manifestation?

Answer 17

Acromegaly

Giganstism

Question 18

Screening test for GHxs

Answer 18

Random IGF1

Question 19

Posterior pituitary hormone

Answer 19

Adh

Question 20

Major function of adh

Answer 20

Osmotic homeostasis

Question 21

Suppressed to max secretion

Answer 21

284-295mOSM

Question 22

Tantamount to hypoosmolality

Answer 22

Hyponat

Question 23

2 types of DI

Answer 23

Neuro

Nephrogenic

Question 24

Test choice for dx of di

Answer 24

Water deprivation test

Question 25

Administration of additional adh has no effect on water absorption

Answer 25

Nephrogenic DI

Question 26

Neurogenic interpretation?

Answer 26

Uosm (before test) < posm | Uosm (after test) 50%increase

Question 27

Thyroid hormones

Answer 27

TRH TSH T3/4

Question 28

3 (unusual sites) where trh is produced

Answer 28

Pancreas Prostate and testis Myocardium

Question 29

Carries specific info for binding of tsh

Answer 29

B subunit

Question 30

Patient has tsh of 0.3?

Answer 30

Normal (0.5-5)

Question 31

Steps in thyroxine formation

Answer 31

``` Active teansport Iodinatiin Coupling Lysis Secretion Deiodination ```

Question 32

Thyroid fn tests

Answer 32

Tsh T3 and t4 Others: TRH, t3-up, rT3, TG, TAb

Question 33

Most commonly used tsh assay

Answer 33

3rd gen

Question 34

Tsh assay can identify ALL hyper/hypothy except?

Answer 34

Hypothalamus and pituitary damage; Thyroid hormone resistance Interference of hypothalamus d/t drugs

Question 35

100% from the thyroid gland

Answer 35

T4

Question 36

T4 is 15.8?

Answer 36

High, 5.5-12.5

Question 37

Laboratory pheochromocytoma measurements

Answer 37

Pmet | Plasma catecholamines

Question 38

High prob in PMet when?

Answer 38

``` Normeta = >400 Meta = 236 ```

Question 39

Pharma test for pheochromo

Answer 39

Clonidine (suppression) | Glucagon (stimulatory)