Lungs and Breast

Question 1

diagnosis for pseudorosettes

Answer 1

metastatic adenocarcinoma

Question 2

peripheral mass in the left upper lobe. what histochemistry?

Answer 2

p63

Question 3

physical exam shows hirsutism and moon facies; lymphocytes with molding. what dx?

Answer 3

small cell carcinoma

Question 4

mass circumscribing the right main bronchus, extending to the lumen. dx?

Answer 4

carcinoid tumor

Question 5

long standing ulcerative colitis. round masses in both lungs. what immunohistochemistry?

Answer 5

TTF-1

Question 6

history of alcoholism. thoracocentesis shows emphysema. what cells are predominant?

Answer 6

lymphocytes

Question 7

most powerful stimulator of smooth muscle spasm

Answer 7

TNF-a

Question 8

released from mast cells resulting in increased prermeability

Answer 8

bradykinin

Question 9

coal miner; reveals black lung; the coal trapped is sequestered by what cells?

Answer 9

fibroblasts

Question 10

coin lesion. dx?

Answer 10

hamartoma

Question 11

sputum reveals acid fast bacilli. resembles what?

Answer 11

miliary TB

Question 12

bronchoscopy discloses obstruction of the LEFT main bronchus. what tumor markes?

Answer 12

p63

Question 13

most frequent form of extrapulmoo TB

Answer 13

scrofula

Question 14

upper truncal obesity and depression; displays hilar mass; what cytologic features?

Answer 14

NE granules

Question 15

barrel chest, hyperresonance on percussion and clubbing of digits. dx is emphysema. what histopathology?

Answer 15

destruction of the walls of airspaces without fibrosis

Question 16

Q fever?

Answer 16

coxiella burnetti

Question 17

what time frame?

Answer 17

4-5th day

Question 18

least increased risk of lung CA

Answer 18

arsenic

Question 19

filariform larval form, hyperinfection syndrome

Answer 19

strongyloides stercoralis

Question 20

primary effusion lymphoma

Answer 20

HHV8

Question 21

emphysema associated w scarring

Answer 21

irregular

Question 22

mesothelioma patterns?

Answer 22

epithelial pattern

Question 23

cystic fibrosis

Answer 23

pseudomonas aeruginosa

Question 24

multinucleated giant cells

Answer 24

RSV

Question 25

kidney shows membranoproliferative glomerulonephritis

Answer 25

good pastures syndrome

Question 26

coating of what forms the ASBESTOS body

Answer 26

iron

Question 27

leukemia on chemotherapy. open lung demonstrates viral pneumonia. what histopath expected on px?

Answer 27

confluent areas of caseous necrosis

Question 28

Strep pneumo

Answer 28

scar formation

Question 29

aspirin?

Answer 29

bronchospasm

Question 30

aspergillosis features?

Answer 30

45 degrees regular branching points

Question 31

breast shows lobular carcinoma in situ. decreased expression of what proteins?

Answer 31

E cadherin

Question 32

BRCA1 promotes what cell function?

Answer 32

DNA repair

Question 33

most likely cause of galactorrhea?

Answer 33

pituitary adenoma

Question 34

dx for sarcomatous stroma in the breast?

Answer 34

medullary CA

Question 35

jelly like tumor in the breast. dx?

Answer 35

colloid CA

Question 36

+ for HEr2/nue but (-) for ER PR

Answer 36

invasive ductal CA

Question 37

single file columns in the breast. what dx?

Answer 37

invasive ductal CA

Question 38

biopsy shows malignant ductal epithelial cells. what therapy?

Answer 38

estrogen receptors

Question 39

painful swelling of the breast. most commonly seen in the ff groups?

Answer 39

women of reproductive age

Question 40

not a feature of BRCA1 mutation

Answer 40

ER positive reactivity

Question 41

adaptive response of the breast?

Answer 41

metaplasia

Question 42

least likely dx for bloody discharge?

Answer 42

phyllodes tumor

Question 43

also known as Zuska

Answer 43

periductal mastitis

Question 44

changes w non proliferative breast changes?

Answer 44

radial scar

Question 45

not a feature of ILC

Answer 45

glandular formation

Question 46

mammary CA, risk factors?

Answer 46

family history

Question 47

mammographic calcification is common

Answer 47

DCIS

Question 48

medullary CA

Answer 48

solid syncytium like sheets