Intro to Nervous system Flashcards

1
Q

What does the axon carry

A

Electrical signals

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2
Q

What is released from presynaptic terminals

A

Neurotrasmitters

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3
Q

What neurotransmitter is exclusively excitatory

A

Glutamate

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4
Q

What neurotransmitter is inhibitory

A

GABA

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5
Q

What neurotransmitter is both

A

Acetylcholine

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6
Q

Indirect neurotransmitters act through

A

intracellular second messengers. Usually takes longer and lasts longer

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7
Q

What are examples of voltage gated chanels

A

Voltage gated Na+ channels; lidocaine

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8
Q

Wha are examples of ligand gated channel

A

Glutamate (AMPA)

Nicotinic ACh receptors

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9
Q

What is Metabotropric

A

they are not directly linked to ion channels

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10
Q

What is ionotropic

A

Action is immediate and brief

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11
Q

What is an autoreceptor

A

receptor on an axon terminal through which the neurons own NT can influence the function the the terminal.
Ex; D2 receptor

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12
Q

What is a heteroreceptor

A

receptors on an axon terminal through which neurotransmitters from other neuronal types can influence the function of the terminal

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13
Q

What are three examples of catecholamines

A

Dopamine
Norepinephrine
Epinephrine

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14
Q

Cathecolamines are related to

A

Drugs of abuse
psychiatric disorder
Autonomics

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15
Q

what is DOPA

A

Dihydroxyphenalanine

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16
Q

What converts Tyrosine to DOPA

A

Tyrosine hydroxylase

17
Q

What converts DOPA to DA

A

Aromatic amino acid decarboxylase

18
Q

What is the transporter on vesicles

A

VMAT; Vesicular monoamine transporter

19
Q

what is MAO

A

Monoamine Oxidase; breaks down Dopamine (DA)

20
Q

What is DBH

A

Dopamine Beta Hydroxylase

21
Q

What converts DA to NE

A

DBH

22
Q

alpha 2 receptor is pre or post

A

Presynaptic

23
Q

What are two post synaptic receptors

A

alpha

Beta

24
Q

What about serotonin

A

Not a catecholamine
Sleep
Depression
Migrane headaches

25
Q

Serotonin is the same thing as

A

5-hydroxytryptamine

26
Q

What is the precursor to serotonin

A

tryptophan

27
Q

What is another name for a ligand-gated receptor

A

Ionotropic

28
Q

What type of receptor is not directly linked to ion channel

A

Metabotropic