4.1 Central Neuraxial Blocks - Spinal Flashcards

(65 cards)

1
Q

Absolute contraindications for spinal anaesthesia

A

Absolute contraindications for spinal anaesthesia
include

  1. patient refusal,
  2. raised intracranial hypertension,
  3. neurological disease of indeterminate origin,
  4. coagulopathy,
  5. severe hypovolaemia
  6. local infection.
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2
Q

Relative contraindications

A

Relative contraindications include

  1. systemic sepsis,
  2. surgery of indeterminate duration,
  3. arthritis,
  4. kyphoscoliosis
  5. previous lumbar surgery.
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3
Q

Spinal and MS patients

A

Central neuraxial block in patients with multiple sclerosis is
controversial. There is no clinical study which has shown that spinal
anesthesia worsens pre-existing neurological disease. Perioperative
surgical stress may exacerbate the condition, and hence a central
neuraxial block may be preferred

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4
Q

Spinal cord has three coverings

A

Dura mater
Arachnoid mater
Pia mater

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5
Q

Dura mater

border

A

(outermost) extends from foramen magnum to S2.

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6
Q

Arachnoid mater

A

Arachnoid mater (middle) extends to S2.

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7
Q

Pia mate

A

Pia mater (innermost) ends in the filum terminale

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8
Q

Supraspinous ligament

A

Supraspinous ligaments extend from
C7 to sacrum
connecting the tips of
the spinous processes.

Above C7, they are called the ligamentum nuchae.

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9
Q

How are the spinous processes connected

How are laminae connected

How are vertebral bodies held together

A

The spinous processes are
interconnected by the interspinous ligaments.

The laminae are connected by the ligamentum flavum.

The vertebral bodies are held together by the anterior and the posterior longitudinal ligaments.

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10
Q

Structures pierced while performing

a spinal anaesthetic via midline

A

Structures pierced while performing a spinal anaesthetic via midline approach are

1 skin

2 subcutaneous tissues

3 supraspinous ligaments,

4 interspinous ligaments

5 ligamentum flavum

6 dura mater

7 subdural space

8 arachnoid mater

and

9 subarachnoid space.

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11
Q

Structures pierced while performing
a spinal anaesthetic via paramedian approach

what is not pierced vs midline

A

However, via the paramedian approach
all the above structures are
encountered
except the

supraspinous
and
interspinous ligaments.

1 skin

2 subcutaneous tissues

3 ligamentum flavum

4 dura mater

5 subdural space

6 arachnoid mater

and

7 subarachnoid space.

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12
Q

Spinal nerves

How many

Do each have 2 components?
what are those componenets

A

1
Thirty-one pairs of spinal nerves
arise from the spinal cord with
anterior motor and posterior sensory roots.

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13
Q

How are the spinal nerves named

From vertebral body above or below

Does this differ anywhere

A

The spinal nerves are named
as per the intervertebral foramen
from which they exit.

In the cervical region,
they are named according to the
lower cervical vertebral body

(C3 emerges from intervertebral foramen
formed by C2 and C3),

but in the
thoracic and lumbar region
they are named

according to the
upper vertebral body

(L3 emerges from intervertebral
foramen formed by L3 and L4).

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14
Q

What happens dorsal nerve roots

A

The dorsal nerve roots
divide into two or three
bundles during their exit

and

redivide further before forming
dorsal root ganglia.

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15
Q

What happens ventral roots

A

Most ventral nerve roots exit
as a single bundle,

explaining the slower onset of
motor blockade because
of smaller surface area for
local anaesthetic action.

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16
Q

What factors affect spread in SA space

A

The factors affecting the spread of
local anaesthetic in subarachnoid
space include the following.

  1. Drug factors
  2. Patient factors

3 Technique

Concentration has no effect 
on the spread of local anaesthetic, 
as a new concentration is 
formed after mixing 
with the cerebrospinal fluid (CSF).
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17
Q

Drug factors

A
Drug factors: 
baricity, 
volume, 
specific gravity 
and dose of local
anaesthetic.
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18
Q

Patient factors

A

Patient factors:
raised intra-abdominal pressure
(pregnancy, obesity, ascites),

spinal column anatomy,
patient position and
patient height.

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19
Q

Technique

A

Technique:

direction of the needle bevel and site of injection.

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20
Q

Effect of Epinephrine and phenyl

A

Epinephrine and phenylephrine
are both vasoconstrictors.

They prolong the duration of action
of local anaesthetic
by decreasing their systemic absorption.

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21
Q

Risk of Epinephrine

A

Because of its vasoconstrictive properties,

epinephrine may cause anterior spinal artery ischaemia.

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22
Q

Risk of phenyl

A

The risk of transient neurological symptoms (TNSs) has been shown to
increase with the use of phenylephrine.

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23
Q

Clonidine effect on SAB

A

Clonidine prolongs both sensory and motor blockade.

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24
Q

Effect of AChI on SAB

(how exert effect)

problems

A

Acetylcholinesterase inhibitors
like neostigmine

exert their effect by increasing
acetylcholine and nitric oxide.

However, their use is limited
by side effects such as 
nausea, 
vomiting, 
agitation, 
bradycardia,
restlessness and 
lower-limb weakness.
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25
The risk factors for hypotension following spinal anaesthetic include 9
The risk factors for hypotension following spinal anaesthetic include 1 obesity (high body mass index) 2 pre-existing hypertension 3 hypovolaemia 4 age > 40 years 5 combined general and spinal anaesthetic 6 chronic alcohol consumption 7 emergency surgery 8 high sensory blockade 9 addition of vasoconstrictor to local anaesthetic solution.
26
Hypotension during spinal What agents are best
Combined alpha and beta agonists are superior to pure alpha agonist in treating hypotension, and ephedrine is currently the drug of choice. Phenylephrine can be used, especially if tachycardia is present.
27
Do Fluids help hypotension
Coloading of fluids at the time of induction has been shown to be superior to the prior infusion of fluids.
28
How may position help / affect hyptotension What may be helpful
Reverse Trendelenburg position may stop the cephalad anaesthetic spread, but may lead to marked hypotension because of venous pooling in lower limbs. Flexion of the operation table may be helpful by elevating the legs but preventing cephalad spread of local anaesthetic.
29
Appropriate sensory levels of blockade for common surgeries are as follows: Caesarean section/upper abdominal surgery gynaecological and urological surgeries vaginal delivery of foetus transurethral resection of prostate lower extremity surgery with tourniquet perineal surgery
Appropriate sensory levels of blockade for common surgeries are as follows: Caesarean section/upper abdominal surgery – T4 gynaecological and urological surgeries – T6 vaginal delivery of foetus – T10 transurethral resection of prostate – T10 lower extremity surgery with tourniquet – T10 perineal surgery – S2–S5.
30
Risk factors for bradycardia with spinal anaesthetic
1 ASA class 1 2 prolonged PR interval (heart blocks) 3 preoperative beta-blocker therapy 4 male gender 5 baseline heart rate < 60 bpm 6 sensory block above T5 7 younger age groups (age < 40 years)
31
High spinal Where does it affect
A high spinal block does not affect the cervical segments usually.
32
Affect of High spinal on respiration (expiration)
High spinal block paralyses the abdominal and intercostal muscles affecting forced expiration. Therefore, there is a decrease in expiratory reserve volume, peak expiratory flow and maximum minute ventilation (all forced expiratory volumes).
33
Affect of High spinal on respiration (inspiration) abg affect does dyspnoea require intubation
There is relative sparing of phrenic nerve and cervical area. Hence, inspiration is minimally affected. Arterial blood gas measurements do not change in a spontaneously breathing patient. Inability to feel the chest wall may result in dyspnoea. This is addressed by reassurance (not intubation).
34
Pencil-point needles
Sprotte and Whitacre require more force to insert than bevel-tip needles, they provide better tactile sensation of the layers of the ligaments encountered
35
Needles with cutting bevels
Pitkin (short cutting bevel) | Quincke (medium cutting bevel)
36
Needle with non-cutting bevel
Greene needle
37
How can be pdph reduced with regards to needle
incidence of post-dural puncture headache (PDPH) can be reduced by directing the bevel of the needle longitudinally.
38
what is the benefit of an introducer where is it placed
Spinal needles with introducers help by preventing contamination of CSF with epidermis, which may lead to formation of dermal spinal tumors. The introducer is placed in the interspinous ligament.
39
The Taylor approach where what position needle insertion direction
The Taylor approach is a paramedian approach at L5–S1 interface, which is the largest interspace. It can be done in the sitting, prone or lateral positions. The needle is inserted 1 cm inferior and 1 cm medial to the posterior superior iliac spine and directed at an angle of 45°–55° cephalad.
40
Intrathecal additives Opiods (and LA - how work)
Opioids act synergistically along with local anaesthetics in intrathecal space by binding to μ-opioid receptors.
41
Issue with morphine vs fentanyl
Morphine may cause delayed respiratory depression (24 hours), whereas lipophilic opioids like fentanyl and sufentanil cause immediate respiratory depression (20–30 minutes).
42
How does fentanyl affect block
Small doses of fentanyl intensify the blockade without prolonging it
43
Clonidine affect on block only when given intrathecal?
Clonidine intensifies and prolongs both sensory and motor blockade. This effect is seen with intrathecal, oral (premedication) or intravenous route of clonidine.
44
Neostigmine affect on block
Neostigmine, an acetylcholinesterase inhibitor, increases the availability of endogenous acetylcholine. Activation of acetylcholine receptors is thought to contribute to an endogenous form of analgesia. However, it is not used because the incidence of nausea and vomiting is high
45
sequence of blockade of nerve fibres is as follows
sequence of blockade of nerve fibres is as follows: ``` B fibres (preganglionic sympathetic) > C fibres (cold sensation) > Aδ (pinprick) > Aβ (touch) > Aα (motor) ```
46
How is nerve blockade recovered
The recovery is in the reverse order. This explains one of the reasons for the zone of differential blockade in spinal anaesthesia: sympathetic block is two segments higher than sensory block, which is two segments higher than motor blockade. These zones of differential blockade remain constant during emergence from spinal anaesthetic.
47
zone of differential blockade in spinal anaesthesia
zone of differential blockade in spinal anaesthesia: sympathetic block is two segments higher than sensory block, which is two segments higher than motor blockade. These zones of differential blockade remain constant during emergence from spinal anaesthetic.
48
What is the CSF density Does it change
The density of CSF varies from 1.00033 g/mL to 1.00067 g/mL. It decreases with increase in temperature.
49
What is Baricity
Baricity is ratio of density of local anaesthetic to CSF.
50
Hyperbaric vs CSF How Duratin
Hyperbaric solutions have greater density to CSF. Local anaesthetics are made hyperbaric by adding glucose 50–80 mg/mL. Hyperbaric solutions have a shorter duration of action than plain solutions.
51
Isobaric solution hypobaric are
Isobaric solutions have the same density as CSF whereas hypobaric are less dense than CSF. Local anaesthetics are made hypobaric by adding distilled water. Hypobaric anaesthetic solution may be used for rectal and perineal surgery in lateral decubitus or prone jackknife position
52
Specific gravity Of LA
Specific gravity is the ratio of density of a substance to the density of water. Local anaesthetics behave as isobaric solution if the density of the solution is within the mean of plus or minus the standard deviation of density of CSF.
53
Useful tips with Baricity position type block with hyper supine how is spread how hypobaric duration of hyper v iso
1 Hyperbaric and hypobaric solutions can be made to spread by altering patient position. 2 Hyperbaric solutions allow for providing a saddle block. ``` 3 In a supine patient, spread of a hyperbaric solution is the maximum, followed by isobaric solutions, while it is the least with hypobaric solutions. ``` 4 Hypobaric solutions are not available commercially and must be prepared at bedside. 5 Hyperbaric solutions have a shorter duration of action than plain solutions.
54
PDPH Incidence Expert using non cutting
Incidence is < 1% if procedure is performed by an expert using noncutting needles (Whitacre or Sprotte).
55
PDPH incidence in OBS
Incidence is higher in the obstetric population (1.7%), since the procedure is technically difficult (exaggerated lordosis) and pregnant patients may not be able to sit very still for the procedure.
56
Dural tear with a tuohy | PDPH incidence
Should a dural tear happen using a Tuohy needle (16 G is usually used for adults), then 50%–80% of those patients go on to develop PDPH.
57
PDPH higher with quincke or whitacre
Higher with cutting needles (Quincke) than with non-cutting needles (Whitacre or Sprotte).
58
mechanism in the development of PDPH includes 3 mech
Loss of cerebrospinal fluid Cerebral vasodilatation Raised intracranial pressure The loss of CSF from the intrathecal space: this leads to intracranial hypotension to start with, causing the sagging of cranial structures in upright position, resulting in headache. Compensatory cerebral venodilatation (in keeping with the Monro– Kelly doctrine, which states that the sum of volumes of the brain, CSF and intracranial blood is constant). Raised intracranial pressure: secondary to cerebral venodilatation
59
Typical features of PDPH are as follows. Hx Onset
Typical features of PDPH are as follows. ``` 1 History of a dural puncture (following spinal) or a possible dural tap (following epidural). ``` 2 Onset is usually delayed (12–48 hours) but can be seen up to 5 days after a procedure.
60
Typical features of PDPH are as follows. Position distribution a/w
3 Headache is typically positional in character (most severe in upright position, while decreases with patient recumbent). an increase in severity of the headache on standing is the sine qua non of PDPH. 4 Is almost always bilateral in distribution. ``` 5 Associated symptoms of nausea, vomiting, neck stiffness, visual/auditory disturbances or cranial nerve involvement. ```
61
PDPH RF Patient-related 4
Young adults (vs elderly) Female sex (vs males) Obstetric patients (vs nonobstetric patients) History of previous headaches
62
Procedure-related RF PDPH
Larger-gauge needles (vs finer needles) Cutting needles (vs non-cutting) Higher number of dural punctures Insertion of needle bevel perpendicular to the direction of fibres of ligamentum flavum (cutting rather than splitting) Non-expert operator Dural puncture following epidural than a spinal (bigger defect)
63
PDPH w/ Paramedian Cathter with puncture?
paramedian approaches may allow better sealing of defects, lowering the incidence of PDPH. Recent evidence suggests that threading a catheter into the subarachnoid space may reduce the incidence of PDPH.
64
Management of post-dural puncture headache Cons + pharma
Conservative bed rest, hydration, abdominal binders Pharmacological paracetamol, non-steroidal anti-inflammatory drugs, codeine strong opioids (as temporary measure) cerebral vasoconstrictors: caffeine, methylxanthine, theophylline 5-HT1 agonist: sumatriptan adrenocorticotropic hormone
65
Management of post-dural puncture headache Interventional
Interventional intrathecal opioids epidural saline epidural blood patch (considered ‘gold standard’): success rate is 70%–90%