ENDOCRINE Flashcards

1
Q

What causes type I diabetes?

A

-pancreatic insufficiency of insulin production

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2
Q

What causes type II diabetes?

A
  • hyperglycemia
  • insulin resistance
  • impaired insulin secretion
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3
Q

Risk Factors for Type 1 DM

A
  • presence of specific protein that forms antibodies
  • family hx
  • dietary factors
  • type 1 or 2 DM in any 1st degree relative
  • increased risk if father has DM
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4
Q

Risk Factors for Type 2 DM

A
  • FHx
  • obesity
  • ethnicity (AA, Hispanic, Native American)
  • GDM
  • triglyceridemia or low HDL
  • impaired glucose tolerance/fasting glucose
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5
Q

How is DM diagnosed?

A
  1. sxs of DM + casual glucose > 200
  2. fasting plasma glucose > 126
  3. 2 hour post prandial oral glucose tolerance test >200
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6
Q

How often should HgbA1c be tested? What is the goal level?

A

-q3 months and goal

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7
Q

How often should DM patients get an eye exam?

A

yearly

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8
Q

How often should DM pts have cholesterol checked? What is the goal?

A
  • yearly
  • LDL 40M, >50W
  • TG
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9
Q

How often should microalbuminuria be checked? What is the goal level?

A
  • yearly

- goal 30)

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10
Q

How often should BP be checked in DM pts? What is the goal level?

A

-every visit

-

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11
Q

What are some potential complications of DM?

A
  • nephropathy
  • chronic skin infxs
  • neuropathy: peripheral neuropathy (monofilament test)
  • ocular: diabetic cataracts, retinopathy
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12
Q

Symptoms:

  • Fatigue, lethargy, weakness
  • Cold intolerance
  • Weight gain
  • Myalgias, arthralgias
  • Constipation, menstrual changes
  • Hair loss
A

Hypothyroidism

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13
Q

Symptoms:

  • Polyuria
  • Polyphagia
  • Polydipsia
  • Weight loss
  • Look ill
  • Decreased C-peptide
A

Type 1 DM

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14
Q

Symptoms:

  • Weight gain
  • Menstrual changes
  • Hirsutism
  • HTN
  • Easy bruising, proximal muscle weakness
  • Decreased libido
A

Cushing Dz

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15
Q

Symptoms:

  • Nervousness, emotional lability
  • Irregular menses
  • Sweating, heat intolerance
  • Fatigue
  • Increased appetite, weight loss
  • Diarrhea
A

Hyperthyroidism

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16
Q

Symptoms:

  • Polyuria
  • Polydipsia
  • Polyphagia
  • Infections
  • Blurred vision
  • Peripheral neuropathy
A

Type 2 DM

17
Q

Signs:

-Painless, symmetric goiter

A

Hashimoto’s thyroiditis

18
Q

Signs:

  • Dry, coarse skin, brittle nails, coarse hair
  • Periorbital and peripheral edema
  • Delayed reflexes, slow speech
  • Bradycardic
  • Muscle cramps, stiffness
A

Hypothyroid

19
Q

Signs:

  • Obesity, moon face, increased adipose tissue in neck and trunk
  • Thin skin, purple striae on skin, acne
  • HTN
A

Cushing Dz

20
Q

Signs:

  • Goiter
  • Warm, moist skin
  • Hair loss
  • Tachycardia at rest, hyperreflexia
  • Exophthalmos
A

Hyperthyroidism

21
Q

What are the lab results for hyperthyroidism?

A
  • low TSH/TRH

- elevated T4

22
Q

Lab Results for Hypothyroidism

A
  • high TSH

- low T4

23
Q

Labs for Cushing Dz

A
  • excretion of free cortisol in the urine >125 ug/dL in 24 hr
  • dexamethasone suppression test