4.1.1 disease Flashcards

(47 cards)

1
Q

what are the two bacterial diseases to know

A

animals: tuberculosis
plants: ring rot

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2
Q

what are the three viral diseases to know

A

HIV / AIDS
tobacco mosaic virus
influenza

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3
Q

what are the two protista diseases to know

A

malaria (plasmodium) and tomato/potato late blight

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4
Q

what are the two fungal diseases to know?

A

athletes foot and black sigatoka

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5
Q

how can pathogens cause harm?

A

through directly damaging tissues or through release of toxins

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6
Q

outline tuberculosis

A

a bacterial disease which affects humans. transmitted through ariborne droplets. cause harm by damaging lung tissue and suppressing the immune system. cured using antibiotics and prevented through vaccination

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7
Q

outline ring rot

A

bacterial disease which infects potatoes, tomatoes and aubergines. it damages leaves, tubers, and fruit. transmitted through infected tubers and micropropogation of plantlets from infected plants. reduces crop yield.

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8
Q

what is a virus

A

a non-living infectious agents. smaller than bacteria and consist of genetic material (DNA or RNA) surrounded by protein. replication occurs within the host cell by taking over the host’s biochemistry to reproduce. many evolve and adapt to their host

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9
Q

outline HIV / AIDS

A

transported around the blood until it attaches to a protein on the T helper cells. HIV positive is when a person is infected. AIDS is when the replicating viruses in the helper T cells interfere with normal immune function. when T helper cells are destroyed by the virus, the host is unable to produce adequate immune responses to other pathogens so is left vulnerable. spread through direct contact of bodily fluids

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10
Q

outline influenza

A

infects the ciliated epithelial cells of the gaseous exchange surfaces. transmitted by airborne droplets.

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11
Q

outline TMV

A

infects plants, causes damage to leaves reslting in mosaic pattern, damages flowers and fruits too. damage prevents plant from growing. transmitted by direct contact or fomites

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12
Q

what are protista?

A

eukaryotes which are unicellular, or cells grouped in colonies. pathogenic protista are parasites and are usually transmitted by a vector.

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13
Q

outline malaria

A

protoctista disease caused by Plasmodium, which is spread to humans through female anopheles mosquito vectors. plasmodium reproduces sexually and asexually within the host. passed by biting mosquitos. Plasmodium infects the red blood cells, the liver, and the brain. no cure.

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14
Q

outline potato blight

A

a fungus-like protists which causes potato blight and tomato late blight. has hyphae which enter plant and damage leaves and fruit. transmitted by spores that travel on the wind or by animals and insects.

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15
Q

what are fungi

A

eukaryotes that cause many plant diseases. when they reproduce they produce millions of spores which spread huge distances

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16
Q

outline black sigatoka

A

fungal disease that infects bananas. hyphae damages the leaves making them black which prevents photosynthesis. transmitted by spores from one plant to the next through the wind. can be killed by fungicides

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17
Q

outline athletes foot

A

only infects humans, a type of ring worm that thrives in warm damp regions like between toes. causes skin to crack and to become scaly leading to itchiness and soreness. spread by direct contact or fomites. curable with antifungal cream

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18
Q

what are the three direct modes of transmission?

A

direct contact- touching, kissing, sexual contact
inoculation: animal bites, sharing needles, cuts in skin
ingestion- drinking and eating contaminated water and food

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19
Q

what are the three indirect modes of transmission

A

vectors- transfer communicable diseases from one host to another
fomites: inanimate objects
droplet inhalation- minute droplets of saliva and mucus inhaled from others.

20
Q

what barrier defences do plants have?

A

bark, waxy cuticle, cellulose cell wall, stomatal closing

21
Q

outline plant responses to infection

A

1) antibacterial chemicals and proteins- to trigger cell wall fortification.
2) plant produces callose- highly branched polysaacharide which is deposited between cell walls and membranes, they act as a barrier to prevent pathogen spread. lignin is added to strengthen the barrier. Callose blocks sieve plates in the phloem, sealing off the infected part.

22
Q

outline non-specific animal responses to infection

A

skin, blood clotting, mucous membranes, lysozymes, expulsive reflexes, inflammation, fevers

23
Q

outline blood clotting as a non-specific primary defence

A
  • skin is broken
  • platelets are activated
  • platelets release substances
  • substances activate enzyme thromboplastin
  • causes production of fibrin fibres
  • form a mesh over wound (clot)
  • clot dries to a scab
24
Q

outline inflammation as a primary non-specific defence

A
  • mast cells release histamine
  • leads to redness and swelling
  • histamine makes capillaries more permeable so more tissue fluid is made
  • mast cells release cytolines to attract white blood cells (chemotaxis)
  • macrophages detect and engulf pathogen
25
what white blood cells are phagocytes
macrophages and neutrophils
26
explain phagocytosis
1) phagocytes recognise any non-self proteins on the surface of a pathogen 2) phagocyte engulfs this pathogen and encloses it in a vacuole called a phagosome 3) phagosome combines with a lysosome to form a phagolysosome 4) enzymes from lysosome digest and destroy the pathogen 5) this is it for neutrophils but macrophages are more complex 6) when digesting, they combine the pathogens antigens with an MHC to become an APC, antigens now stimulate other cells in the specific immune response.
27
where are lymphocytes made, where fo they mature
B and T created in the bone marrow. B mature in the bone marrow, T mature in the thymus.
28
what are the two specific immune responses?
cell mediated immunity humoral immunity
29
outline primary and secondary antibody responses
on first exposure to a non-self antigen, production of antibodies is necessary and takes about 7-10 days. on later exposure to same antigen the production is immediate due to memory cells.
30
what is an autoimmune disease, give example
when self cells are recognised as non-self. the immune system attacks healthy body tissues causing damage and inflammation. immunosuppressants help treat but they reduce our natural defecnes. e.g. rheumatoid arthritis.
31
structure of an antibody
4 polypeptide chains held by disulphide bridges. Y shaped glycoproteins called immunoglobulins, they bind to a specific antigen on the pathogen. made of two identical chains called the heavy chains and two much shorter chains called the light chains. they bind by a lock and key theory. the binding site is the variable region, the rest is the constant region. hinge region between allows agglutination
32
what are opsonins
antibodies that cover the surface of the pathogen, tagging the pathogen as a taget for phagocytes
33
what are agglutinins
antibodies that cause pathogens with an antigen-antibody complex to clump together making it easier to engulf multiple at once.
34
what are antitoxins
antibodies that bind to toxins produced by pathogens making them harmless
35
what is natural immunity
stimulates the immune system naturally by picking up pathogens from the environment. e.g. across the placenta or breastfeeding
36
what is artificial immunity
through vaccines and antitoxins
37
what is active immunity
when the immune system develops a response to the pathogen itself like getting polio for real
38
what is passive immunity
body receives a natural or artificial antibody or antitoxin directly
39
what is an endemic
always present in the population
40
what is an epidemic
spreading rapidly to a lot of people in a large area
41
what is a pandemic
a worldwide epidemic
42
what is herd immunity
making sure enough people in a population are vaccinated to prevent disease spread. percentages of the pop. needed to be immune varies by disease. 85% for smallpox.
43
what is ring immunity
people living in or working near an outbreak are vaccinated to prevent the disease from spreading. e.g. family of meningitis sufferer
44
what was first discovered antibiotic
penicillin by Fleming. effective against gram + bacteria.
45
how do antibiotics work (many ways)
prevents cell wall synthesis, transcription, translation, DNA synthesis, cell surface membrane function, folic acid synthesis.
46
what are some sources of medicine
sources from microorganisms. extinction means we can't discover more. antibiotics are produced by mircoorganisms.
47
what are some examples of antibioitics from nature?
microorganisms: penicillin and vancomycin Plants: apsirin, digitoxin, quinine