Granule contents Flashcards
1
Q
Hydrolytic enzymes
A
cathespin, lysozyme, phospholipase, glycosidase
digest cell wall components, may act on viral protein coats
2
Q
defensins
A
cationic proteins
NOT an enzyme: a peptide
contains large amounts of arginine in polypeptide form – kills microbes by interacting with microbial membrane to form channels through which metabolites can escape
3
Q
iNOS
A
inducible nitric oxide synthase
stimulated by synergistic action of IFN-gamma and TNF
combines oxygen with guanidine from arginine to produce NO
