review deck Flashcards
location of B2 receptors
smooth mm (uterus and bronchiolar)
liver (glycogenolysis)
kindey (renin secretion)
of the choline esters, which are mainly muscarinic vs nicotinic?
muscarinic- methacholine, bethanechol
nicotinic- carbachol
PO vs. topical uses of pilocarpine
PO- xerostomia
topical- glaucoma
how can anticholinergic substances cause an increase in body temp?
decreased sweating leads to increased body temp
class and MOA of benztropine
synthetic muscarinic antagonist (anticholinergic) for the treatment of extrapyramidal sx
treatment for OD of non depolarizing NM blockers
ACHE Inhibitors (neostigmine)
duration of action for the non depolarizing NM blockers (4)
short- pancuronium
medium- rocuronium and vecuronium
long- mivacuronium
hemicholinium
vesmachol
botulinum toxin
hemicholinium- decreases choline transport into neuron
vesmachol- decreased ACH packaging in vesicles
botox- decreases release of ACH from vesicles into synapse