Fungi Flashcards

1
Q

Fungii cell wall

A

Complex consists of: chitin, glucan, and mannan

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2
Q

Nonseptate Hyphae

A
  1. No cross walls
  2. Broad with irregular width
  3. Broad angle of branching
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3
Q

Septate Hyphae

A

Cross walls

Width fairly regular (tube-like)

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4
Q

Key Dimorphic Fungi

A
  1. Histoplasma
  2. Blastomyces
  3. Coccidioides
  4. Sporothrix
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5
Q

Body Heat Changes Shape

A

Dimorphic fungi

Blastomyces

Histoplasma

Coccidioides

Sporothrix

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6
Q

Pt with blotchy hypopigmentation of skin

KOH scraping shows “spaghettie and meatballs

A

Malassezia furfur

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7
Q

Trichophyton

A

Dermatophytes that infect skin, hair and nails

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8
Q

Microsporum

A

Dermatophytes that infect hair and skin

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9
Q

Epidermophyton

A

Dermatophytes that infect nails and skin

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10
Q

Pt with subcutaneous/lymphocutaneous mycetoma

Gardener, florist, basket weaver

Cigar-shaped yeasts in pus

A

Sporothrix schenckii

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11
Q

Histoplasma regions

A

Eastern Great lakes, Ohio, Mississippi, and Missouri River Beds

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12
Q

Histoplasma found in

A

Soil enriched with bird or bat feces

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13
Q

What cells is Histoplasma found in

A

Reticuloendothelial cells

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14
Q

Histoplasma causes

A

Pneumonia like

Hepatosplenomegaly

Lesions have a tendency to calcify as they heal

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15
Q

Coccidioides region

A

Southwestern US

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16
Q

Histoplasma tissue form

A

Small intracellular yeast with narrow neck on bud

NO CAPSULE

17
Q

Coccidioides tissue form

A

Spherules with endospores

18
Q

Valley fever

A
  1. Due to Coccidiodes
  2. Desert bumps (erythema nodosum)
  3. Arthritis
  4. Pulmonary lesions have a tendency to calcify
19
Q

Aspergillus predisposing conditions

A

Asthma, CF

Fungus ball

Neutropenia, CGD, CF, burns

20
Q

Cryptococcus source

A

Soil enriched with pigeon dropping

21
Q

Pigeon breeder with acute pulmonary symptoms

A

Cryptococcus

22
Q

Hodgkins/AIDs pt with meningitis

A

Cryptococcus

23
Q

How do you stain Cryptococcus

A

India Ink

24
Q

What infection occurs in ketoacidotic diabetic patients and leukemic patients

A

Mucor

25
Q

Premature infant or AIDs pt with atypical pneumonia

A

Pneumocystis

26
Q

Pneumocystis biopsy reveals

A

Homneycomb exudate and silver-staining cysts

27
Q

Xray of Pneumocystis

A

Ground glass

28
Q

What does Pneumocystis attach to?

A

Type 1 pneumocytes causing excess replication of Type 2 pneumocytes