H&N Malignancy

Question 1

What is your differential diagnosis of diffuse infiltration of salivary gland?

Answer 1

Benign:

• acute / chronic sialedenosis / sialedenitis
• HIV
• granulomatous: TB, sarcoid
• reactive

Benign and Malignant 1’ salivary gland tumours

Other non-salivary gland malignancies: melanoma, lymphoma, mets

Question 2

List benign tumours of salivary glands

Answer 2

• Pleomorphic adenoma (#1)
• Warthin’s tumour (#2)
• Oncocytoma
• monomorphic adenoma
• sebaceous adenoma
• basal cell adenoma
• cystadenoma
• hemangioma
• ductal papilloma

Question 3

List malignant salivary gland tumours

Answer 3

• Mucoepidermoid carcinoma
• Adenoid cystic carcinoma
• Acinic cell carcinoma
• Adenocarcinoma
• Carcinoma ex-pleormorphic adenoma
• SCC

Question 4

What are the HPV strains associated w/ malignancy

Answer 4

16, 18, 31, 33

Question 5

What is your differential diagnosis of a tongue mass?

Answer 5

Benign: granular cell myoblastoma, papilloma

Malignant: SCC, lymphoma, sarcoma

Trauma: pyogenic carcinoma

Infectous: TB, syphillus cancre, verruca vulgaris