Pain Flashcards

1
Q

what is pain

A

an unpleasant emotional and sensory experience associated with tissue damage

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2
Q

What are the three types of pain

A

nociceptive, inflammatory, pathological

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3
Q

What are nociceptors stimulated by?

A

Intense stimuli that is noxious

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4
Q

What are nociceptors

A

peripheral primary sensory afferent neurones

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5
Q

Nociceptors are first order neurons that relay info to second order neurones in CNS, true or flase

A

true

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6
Q

Can nociceptors be stimulated by weal stimuli?

A

Hell-no- it has a high threshold thus only intense stimuli can provoke nociceptors

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7
Q

What is inflammatory pain?

A

Adaptive and protective

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8
Q

What is allodynia?

A

A stimuli that once didn’t produce pain or harm, but now does

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9
Q

Can inflammatory pain be healed by itself?

A

No, it normally requires medication or treatment of some sort

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10
Q

What is pathological pain?

A

Maladaptive with NO PROTECTION

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11
Q

How does pathological pain usually occur?

A

due to a malfunction somewhere in the nervous system

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12
Q

What are alpha delta fibres?

A

mechanical and thermal myelinated nociceptors. This is FIRST pain.

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13
Q

What are C fibre nociceptors?

A

unmyelinated receptors that respond to all stimuli thus bringing about a second pain

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14
Q

Where does transduction of nociceptors occur

A

free nerve endings

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15
Q

Describe the process of sensory neurones

A

stimulated by heat/ mechanical or chemical ways- open ion channels- depolarising receptor - amplitude of potential relative ti intensity of stimulus

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16
Q

What has an afferent and efferent function?

A

Peptidergic polymodal C fibre nociceptors

17
Q

What does the peptide SP do?

A

vasosilation, extravasation of palm proteins, release cytokines and mast cells and sensitizes surrounding nociceptors

18
Q

What is the transmitter between primary afferent and second order neurone?

A

glutamate

19
Q

Where does C and alpha delta fibres terminate?

A

laminae 1 and 2

20
Q

What is it called when ells receive input form only alpha delta fibres?

A

Proprioceptive

21
Q

What 2 sysmtens ascends on the spinal cord

A

spinothalamic tract and spinoreticular tract

22
Q

What neurones do the spinothalmic have

A

alpha delta