Information carriers

Question 1

4 examples of polysaccharide information carriers

Answer 1

Glycoconjugates
N-linked glycan cores
O-linked glycan cores
Glyolipids

Question 2

Glycoconjugate is a complex between what

Answer 2

polysachharide bound to a protein or lipid

Question 3

Viruses, prokaryotic and eurkaryotic cells are covered with carbs in the form of what `

Answer 3

Glycoconjugates

Question 4

name 4 functions of glycoconjugates have

Answer 4

1. Protein folding and protein destination labelling
2. Mediate cell-cell interactions, cell recognition, adhesion and migration
3. Mediate protein-protein and protein-cell interaction
4. Mediate interactions between cells and extracellular matrix

Question 5

Carbs attach to proteins via what

Answer 5

Anomeric carbon (reducing end)

Question 6

How are the N linked Glycoproteins attached

Answer 6

via the amide nitrogens of asparagine residues

Question 7

How are the O linked Glycoproteins attached

Answer 7

attached to hydroxyl groups of serine, threonine or hydroxylysine

Question 8

Many eukaryotic proteins are what

Answer 8

glycosylated

Question 9

N linked oligosaccharides are attached to what

Answer 9

asparagine

Question 10

O linked ogliosaccharides are attached to what

Answer 10

serine and threonine

Question 11

What are the 3 Nlinked glycans

Answer 11

Complex, Hybrid, High Mannose

Question 12

What Pentasaccharide core is common to all Nlinked ogliosaccharides

Answer 12

(add picture)

Question 13

What Pentasaccharide core is common to all Olinked ogliosaccharides

Answer 13

GalNAc–Asn

Alpha bond

Question 14

Erythropoietin is a glycoprotein secreted by what

Answer 14

by the kidney into the blood that stimulates the production of red blood cells

Question 15

Glycosylation of erythropoietin enhances what

Answer 15

stability of the protein in the blood

Question 16

Numerous glycan epitopes are expressed at what ends of N and O linked core glycans

Answer 16

Non reducing ends