Lecture 15 - Micturition Flashcards

1
Q

Filling of the bladder produces a signal via the pudendal nerve, resulting in ______

A

inhibition of the external urinary sphincter (pudendal n. is somatic and therefore voluntary)

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2
Q

Cortex of the brain will stimulate the micturition reflex, and inhibit the ______

A

external urinary sphincter

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3
Q

How do nephrons regulate acid-base balance?

A. Secretion of hormones that change afferent arteriole size, leading to increased acid/base excretion
B. Excrete acids (specificially sulfuric and phosphoric acids)
C. Secrete vasoactive factors to regulate blood flow, thereby changing excretion rates

A

B. Excrete acids

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4
Q

Kidneys produce what two major hormones?

A

Erythropoietic, and 1,25-dihydroxycalciferol (Vit D3)

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5
Q

What is the formula for the urinary excretion rate?

A

Filtration-reabsorption+secretion

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6
Q
Movement of solutes from the Glomerulus to the Bowman's capsule
A. Filtration
B. Reabsorption
C. Secretion
D. Excretion
A

A. Filtration

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7
Q
Solutes not initially filtered, but are placed into the filtrate from the blood.
A. Filtration
B. Reabsorption
C. Secretion
D. Excretion
A

C. Secretion

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8
Q
Removal of filtrate from the nephron
A. Filtration
B. Reabsorption
C. Secretion
D. Excretion
A

D. Excretion

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9
Q
Movement of filtered solutes back into blood.
A. Filtration
B. Reabsorption
C. Secretion
D. Excretion
A

B. Reabsorption

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10
Q

Glomerular hydrostatic and Glomerular osmotic pressure determines GFR. What else is a determinant of GFR?

A

Kf

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11
Q

The three components of the glomerular capillaries contain (positive/negative) charges.

A

negative

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12
Q

This is a change of nephron function before histological changes. It is due to loss of basement membrane (-) charges, resulting in proteinuria.

A

Minimal change nephrophathy

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13
Q

Four factors affecting GFR.

A

Glomerular hydrostatic P
Bowman’s hydrostatic P
Glomerular oncotic P
Bowman’s oncotic P

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14
Q

GFR of a normal, adult male

A

180 L/day

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15
Q

Dilation of the renal pelvis and calyces

A

Hydronephrosis

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16
Q

Filtration fraction is defined as _______.

A

GFR/renal plasma flow

17
Q

Increasing the filtration fraction also increases the _____ oncotic pressure.

A

glomerular

18
Q

Increased arterial pressure will (increase/decrease) GFR

A

increase

19
Q

Increased afferent arteriolar resistance will (increase/decrease) GFR

A

decrease

20
Q

Increased efferent arteriolar resistance will (increase/decrease) GFR

A

increase

21
Q

Formula for renal blood flow

A

(Renal arterial P-Renal vein P)/TVR

22
Q

Sympathetic activation will (increase/decrease) GFR.

A

decrease; the SNS will constrict the arterioles, and decrease blood flow to kidneys

23
Q

Angiotensin preferentially constricts ____ arterioles.

A

efferent

24
Q

Autoregulation acts to prevent (small/large) changes to GFR that would normally occur even with small blood pressure changes.

A

large

25
Q

The juxtaglomerular complex acts to control ______.

A

the dilation of afferent and efferent arterioles

26
Q

Reabsoprtion of NaCl in the _____ stimulates the juxtaglomerular complex

A

ascending limb of loop of Henle

27
Q

Decreased macula densa [NaCl] will result in ____ to afferent arterioles and release of _____ from JG cells.

A

dilation; renin

28
Q

Bladder stretch receptors send signals to the sacral region of the SC via ______, and the signals are conducted back to the bladder via _______.

A

pelvic nerves;

parasympathetic nerves

29
Q

What are the mechanisms by which the kidney affects arterial blood pressure?

A
  1. Short term - excrete sodium and water
  2. Long term - secrete hormones and vasoactive factors