AAW - Drug suffixes Flashcards

1
Q

-azole

A

Ergosterol synthesis inhibitor

e.g. ketoconazole

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2
Q

-bendazole

A

antiparasitic/anthelmintic

e.g. Mebendazole

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3
Q

-cillin

A

Peptidoglycan synthesis inhibitor

e.g. Ampicillin

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4
Q

-cycline

A

protein synthesis inhibitor

e.g. Tetracycline (this binds 30s)

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5
Q

-mivir

A

Neuraminidase inhibitor

e.g. Oseltamivir

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6
Q

-navir

A

Protease inhibitor

e.g. Ritonavir (this one also inhibits P450)

NAVIR TEASE a proTEASE

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7
Q

-ovir

A

DNA polymerase inhibitor

e.g. Acyclovir (used to treat viruses mainly herpes class)

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8
Q

-thromycin

A

Macrolide

e.g. Azithromycin, Erythromycin

ALSO fidaxomycin

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9
Q

-ane

A

Inhalational general anesthetic

e.g. Halothane

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10
Q

-azine

A

Typical antipsychotic

e.g. Thioridazine

and haldol

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11
Q

-barbital

A

Barbiturate

e.g. phenobarbital

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12
Q

-caine

A

Local anesthetic

e.g. Lidocaine

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13
Q

-etine

A

SSRI

e.g. Fluoxetine

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14
Q

-ipramine

A

TCA

e.g. Imipramine, Desipramine

“I’M DES, your Traumatic Care Attendant”

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15
Q

-triptan

A

Serotonin 1B/1D agonist

Sumatriptan (constricts vessels in brain for migraine and reduces trigeminal nerve firings for cluster headaches)

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16
Q

-triptyline

A

also a TCA

e.g. Amitriptyline

“DES is clumsy and trips alot”

17
Q

-zepam

A

Benzodiazepine

e.g. Diazepam

18
Q

-zolam

A

Benzodiazepine

e.g. Alprazolam

19
Q

-chol

A

Cholinergic agonist

e.g. Bethanechol/carbachol (selectively stimulates muscarinic receptors without any effect on nicotinic receptors, can make you pee)

20
Q
  • curium

- curonium

A

Non-depolarizing paralytic

e.g. Atracurium or Vecuronium, Rocuronium

21
Q

-olol

A

Beta-blocker

e.g. Propanolol

22
Q

-stigmine

A

AChE inhibitor

e.g. Neostigmine

23
Q

-terol

A

Beta2-agonist

Albuterol (short), Salmeterol, Formeterol (long)

24
Q

-zosin

A

Alpha1-antagonist

e.g. Prazosin

25
Q

-afil

A

PDE-5 inhibitor

e.g. Slidenafil

26
Q

-dipine

A

Dihydropyridine calcium clannel blocker

e.g. Amlodipine

27
Q

-pril

A

ACE inhibitor

e.g. Catropril

28
Q

-sartan

A

Angiotensin-II receptor blocker

e.g. Losartan

29
Q

-statin

A

HMG-CoA reductase inhibitor

e.g. Atorvastatin

30
Q

-dronate

A

Bisphosphonate (used to treat osteoporosis)

e.g. Alendronate

31
Q

-glitazone

A

PPAR-gamma activator (binds PPAR receptors on fat cells and making them more sensitive to insulin)

e.g. Rosiglitazone

32
Q

-prazole

A

Proton pump inhibitor - treats GERD

e.g. Omeprazole

33
Q

-prost

A

Prostaglandin analog

e.g. Latanoprost

34
Q

-tidine

A

H2-antagonist - inhibits stomach acid production

e.g. Cimetidine

35
Q

-tropin

A

Pituitary hormone

e.g. Somatotropin

36
Q

-ximab

A

Chimeric monoclonal Ab

e.g. Basiliximab

37
Q

-zumab

A

Humanized monoclonal Ab

e.g. Daclizumab