lecture 1 Flashcards
Anton Leeuwenhoek
Believed in spontaneous generation
Factors influencing decreased infection
Better nutrition Antibiotics Improved hygiene Immunizations Safer food and water Better housing
Francesco redi
Bugs on rotting meat was because of fly eggs
John needham
Cloudy broth after boiling cooling then sealing
Lazzaro spallanzani
Sealed then cooled. It was clear.
Louis pasteur
Microorganisms in the air
Germ theory
Inoculum from cow with anthrax injected into healthy mouse. It became ill. Chopped up and injected into another mouse. Became ill.
Epidemic
Incidences of disease within a population that’s above what’s expected
Pandemic
Incidences of disease within the world. Crossed continents.
Endemic
Incidences of disease that’s expected within a population
Outbreak
Incidences of disease that suddenly pops up in a short period of time
Exposure
Infection
Disease
Pathogen that’s close
Invasion and multiplication
Medical condition associated with symptoms
Chain of infection
Pathogen, source, Mode of transmission, entry, susceptible host
What is virulence and how do we measure it?
The ability of a pathogen to cause damage to the host
Mortality rate
Tissue damage
Immunosuppressive
Determinants of virulence
Colonization
Immunosuppression and immune invasion
Intracellular access
Nutrient hijacking
