47. Medullary Thyroid Cancer Flashcards
1
Q
Where does Medullary thyroid cancer occur
A
in the C cells
2
Q
What does medullary thyroid cancer secrete
A
calcitonin and carcinoembryonic antigen
3
Q
medullary thyroid cancer:
- where is the RET proto-oncogene located
- Genetic mutation of RET is seen in _____ & _____ MTC.
A
- chromosome 10
- hereditary and sporadic
4
Q
s/s medullary thyroid cancer
A
painless lump on the front neck
5
Q
testing for medullary thyroid cancer
A
- fine needle aspiration (FNA) biopsy of a thyroid nodule
- blood test if FNA Bx positive (calcitonin ↑, carcinoembryonic antigen (CEA) ↑)
6
Q
medullary thyroid cancer:
describe genetic counseling
A
For Patients with 1st degree relatives, thyroid should be removed before MTC develops
