January 8, 2016 - Medical Management of IHD

Question 1

Anti-Platelet Agents

Answer 1

ASA

Clopidogrel

Tocagrelor

Use two of these together. Will reduce the complications of an MI.

Question 2

Statins

Answer 2

Used to lower cholesterol. Used after an MI to reduce the risk of recurrence.

Can lower cholesterol levels by 50%.

Question 3

PCSK-9 Inhibitors

Answer 3

Used to lower cholesterol.

Can lower cholesterol an additional 50% when taken in combination with statins.

Question 4

ACE Inhibitors

Answer 4

End in -pril.

Used to lower blood pressure. It does this by preventing the conversion of angiotensin I to angiotensin II (which is a vasoconstrictor). Thereby, blood pressure is lowered by reducing SVR.

Question 5

ARB Inhibitors

Answer 5

Ends in -sartan

Lowers blood pressure.

Binds angiotensin receptors on vascular smooth muscle, preventing them from being activated. This lowers BP by reducing SVR.

Question 6

Beta-Blockers

Answer 6

Lowers heartrate and blood pressure.

Blocks beta receptors, preventing epinephrine and norepinephrine from binding. This lowers both HR and BP.

Question 7

Mediterranean Diet

Answer 7

Has been shown to (slightly) reduce CVD events.

Question 8

CVD and Alcohol

Answer 8

Drink alcohol in moderation.

Not more than 2 drinks per day for men or 1 drinks per day for women.

Definitely, do not binge drink by having more than 6 drinks in a 12 hour window.

Question 9

Nitroglycerin and ACS

Answer 9

Acts on smooth muscle and causes vasodilation.

Just because NTG helped, does not mean the condition was ACS. There is a lot of smooth muscle in your body.