Clinical Mycobacteriology Flashcards

1
Q

most common bacteria pathogens

A

m. tuberculosis
m. africanum
m. bovis (bovine bacillusm )
m Bovis Bacille Calmette-Guerin (BCG)

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2
Q

cell wall properties of Mycobacteria

A

high lipid content
waxy coat
lipoarabinomannan

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3
Q

AFB

A
  • binds to carbol fuchsin dye (unable to be removed by acid alcohol
  • acid fastness=resistance to decolorization by acid
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4
Q

ways to check for TB

A
  • mantoux tuberculin skin test
  • booster effect:two step TST testing
  • interferon gamma release assay
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5
Q

signs of tuberculosis

A

cough with sputum
pulmonary parenchyme
fever and wieght loss and IL-1 and TNF alpha

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6
Q

current methods for identification in clinical laboratory

A

Nucelic acid amplification test direct from sputum
automated broth-based culture methods
agar-based culture methods

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7
Q

Signs of lepromatous leprosy, effects

A

demarcated lesion on all partsof body, inbility to mount cellular immunity

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8
Q

Cervical lymphadenitis is common in___

A

children

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9
Q

Acute/bilateral cervical lymphadenitis

A

viral upper resp. tract infect or streptococcal phayngitis

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10
Q

acute unilateral cervical lymphadenitis

A

strep or staph infection

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11
Q

Subacute or chronic unilateral cervical lymphadenitis

A

bartonella (cat strach)

mycobacteria- MTB, MAC, M. scrofulacium

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12
Q

Runyon I

A

photochromogens

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13
Q

Runyon II

A

scotochromogens

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14
Q

Runyon III

A

Nonchromogens

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15
Q

Runyon IV

A

Rapid growers

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16
Q

Runyon I makes and speed

A

yellow-orange pigment only when exposed to light, slow

17
Q

Runyon II makes and speed

A

yellow-orange pigment when exposed to light or dark, slow

18
Q

Runyun III makes and speed

A

no pigment and slow

19
Q

Runyon IV makes and speed

A

no pigment and fast, 5 days

20
Q

Ex. of Runyon I

A

M. kansasiii and marinum

21
Q

Ex. Runyon II

A

M. scrofulaceum

22
Q

Ex. of Runyon III

A

M. avium-intracelluare

23
Q

Ex of Runyon IV

A

M. fortuitum , Mchelonae-abscessus