48 The Impact of Rheumatic Diseases and Their Treatment on Bone Strength Development in Childhood

Question 1

Bone is composed of

Answer 1

70% mineral/inorganic components
30% organic components

Question 2

Accounts for 95% of mineral content of bone

Answer 2

Hydroxyapatite (calcium and phosphorus)

Question 3

Makes up 98% of the organic component of bone

Answer 3

Matrix, which is predominantly Type I collagen

Question 4

___ determines from 50% to 85% of the skele- tal mass

Answer 4

Heredity

Question 5

The process by which the skeleton refreshes itself by working on the same bone surfaces, engaging first in resorption to remove old, damaged bone and then formation to replace the old bone with new, healthy tissue

Answer 5

Bone remodeling