opthalmic drugs

Question 1

what do parasympatholytic agents do to iris

Answer 1

constrict

Question 2

what do symphathomimetics do to iris?

Answer 2

dilate

Question 3

examples of parasympatholytic agents (2)

Answer 3

1. Tropicamide

2. cyclopentolate

Question 4

do sympathomimetics affect accomodation?

Answer 4

no

Question 5

example of sympathomimetic (1)

Answer 5

phenylephrine

Question 6

does tx of viral conjunctivitis include antivirals?

Answer 6

no antivirals ineffective against adenovirus

Question 7

risk assc’d with use of topical steroids in tx of HSV?

Answer 7

1. can exacerbate herpes keratitis,
2. elevate IOP,
3. cause cataracts

Question 8

which PG analogue is preservative free?

Answer 8

tafluprost

Question 9

how do PG analogues fxn for glaucoma?

Answer 9

incr uveoscleral outflow

Question 10

how are beta adrenergic blockers effective for glaucoma?

Answer 10

decr aqueous production

Question 11

which people should not be tx’d with beta antags?

Answer 11

asthma

COPD

Question 12

which drug incr aqueous outflow thru trabecular meshwork

Answer 12

cholinergic agonists

Question 13

what is the safest glaucoma medicine for a pregnant woman

Answer 13

brimonidine (adrenergic agonist)

Question 14

which drug can cause apnea in children

Answer 14

brimonidine

Question 15

if you give systemic meds above recommended doses, are ocular SE likely to be reversible or irreversible?

Answer 15

reversible

Question 16

if you give systemic meds at recommended doses, are ocular SE likely to be reversible or irreversible?

Answer 16

can be irreversible or reversible

Question 17

floppy iris syndrome

Answer 17

Alpha 1 blockers

Question 18

cornea, retina, ON

Answer 18

tamoxifen

Question 19

dose related optic neuropathy

Answer 19

ethambutol

Question 20

corticosteroids can lead to

Answer 20

cataracts, glaucoma

Question 21

irreversible maculopathy

Answer 21

Chloroquine/hydroxychloroquine

Question 22

insidious onset often bilateral nonarryhtmic anterior ischemic optic neuropathy that is irreversible; and corneal changes that are reversible

Answer 22

amiodarone

Question 23

acute angle closure glaucoma irreversible SE

Answer 23

topiramate

Question 24

HMG coa reductase inhibs reversible SE

Answer 24

myopathy, diplopia, ptosis, ophthalmoplegia, cataracts

Question 25

what drug can cause reversible blue color tinge

Answer 25

PDE5 inhibs

Question 26

which drugs can result in ocular SE above recommeded doses (3)

Answer 26

1. digitalis 2. diphenhydantoin 3. thioridazine

Question 27

Corneal/lens opacities

Answer 27

chlorpromazine