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BMed3.2 - Pharmaco > 5. Pharmaco des maladies inf GI & hépatites > Flashcards

5. Pharmaco des maladies inf GI & hépatites Flashcards

1
Q

Sulfasalazine & Mésalazine

A
  • AINS
  • mécanisme indépendant des COX
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2
Q

Azathioprine & Mercaptopurine

A
  • immunosuppresseur
  • incorporation dans acides nucléiques
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3
Q

Anti-TNFa

A
  • inflixumab, adalimumab
  • Ig chimériques anti-TNFa
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4
Q

Inhibiteurs des intégrines

A
  • Natalizumab, Védolizumab
  • Ig monoclonal anti-intégrines
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5
Q

Ribavarine

A

analogue nucléosidique anti-HCV

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6
Q

Interféron alpha

A
  • cytokine avec activité anti-virale, immunomodulatrice et antiproliférative
  • anti-HCV et HBV
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7
Q

Télapravir & Bocéprévir

A
  • inhibiteur peptidomimétique des protéases virales
  • anti-HCV
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8
Q

Sofosbuvir & Ledipasvir

A
  • sofosbuvir : inhibiteur de la polymérase NS5B
  • ledivaspuvir : inhibiteur NS5A
  • utilisation en association
  • anti-HCV
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BMed3.2 - Pharmaco (5 decks)

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