50% Dextrose in Water (D50)

Question 1

Generic/Trade Name

50% Dextrose in Water

Answer 1

D50

Question 2

Generic/Trade Name

D50

Answer 2

50% Dextrose in Water

Question 3

50% Dextrose in Water (D50)

Drug Classification:

Answer 3

Carbohydrate

Question 4

50% Dextrose in Water (D50)

Mechanism of Action:

Answer 4

Raises blood glucose simply by added presence directly into vasculature

Question 5

50% Dextrose in Water (D50)

Pharmacokinetics

Answer 5

• Onset of Action < 1 minute
• Peak Effects = Varies
• Duration of Effect = Varies
• Half-Life = N/A

Question 6

50% Dextrose in Water (D50)

Indications & Contraindications

Answer 6

Indications/Field Use:
• Hypoglycemia

Contraindications:
• Caution Pt.’s with increased ICP

Question 7

50% Dextrose in Water (D50)

Side Effects/Adverse Reactions:

Answer 7

HA, N+V

Anxiety, sweating, dizziness, nervousness, tremor,

HTN, palpitations, arrhythmias, chest pain,

Question 8

50% Dextrose in Water (D50)

Adult & Pedi Dose:

Answer 8

(ADULT): 25g slow IV, IO, repeat PRN

(PEDI): 0.5-1g/kg slow IV, IO

Question 9

50% Dextrose in Water (D50)

Precautions:

Answer 9

• Local venous irritation may occur in smaller veins
• May be diluted 1:1 with sterile water to make D25 for children

Question 10

50% Dextrose in Water (D50)

Drug-Drug Interactions:

Answer 10

None EMS