Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Sobe > Schizophrenia Sutherland > Flashcards

Schizophrenia Sutherland Flashcards

1
Q

What precedes the onset of classical psychosis?

A

Cognitive impairment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the negative symptoms of shcizophrenia?

A

apathy, flat affect, withdrawal, social avoidance, poor motivation, self neglect

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are positive symptoms of schizophrenia

A

Hallucinations (auditory >visual> other), Delusions (paranoid, nihilistic), Odd behavior

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are top three risk factors for schizophrenia?

A

Positive family hx, perinatal complications (infxn), late winter/early spring births

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

When is the onset of schizophrenia?

A

Late teens/20’s (30’s for women

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the most common causes of death for schizophrenia

A

90-95% of pts die of other causes other than suicide, 4-5% (up to 10) die of suicide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the pathophys of schizophrenia?

A

Increased brain dopamine, loss of brain mass, loss of white matter, “neurodevelopmental” disorder

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

T/F: You have an increased risk of having schizophrenia with a 1st degree relative?

A

True; 10-12x higher risk

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

T/F: increased risk of schizophrenia with perinatal complications?

A

True; late winter/early spring, maternal infxns, birth complications, Rh incompatibility, nutritional deficiencies, famine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What do drugs that increase DA do to psychosis?

A

Cause psychosis (hallucinations, paranoia, manic symptoms)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What do drugs that decrease DA do to psychosis?

A

Reduce psychotic symptoms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the mechanisms of PCP (for fun)?

A

Blocks glutamate, which increases DA and increases psychotic symptoms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the effect of schizophrenia on Basal ganglia?

A

Contributes to paranoia and hallucinations. Anti-DA meds also cause motor side effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the effect of schizophrenia on frontal lobe?

A

difficulty planning actions and organizing thoughts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the effect of schizophrenia on limbic system?

A

agitation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the effect of schizophrenia on auditory system

A

auditory hallucinations

17
Q

What is the effect of schizophrenia on occipital lobe

A

difficulties interpreting complex images, recognizing motions, reading emotions on faces

18
Q

What is the effect of schizophrenia on hippocampus

A

difficulty learning and memory formation

19
Q

What are psychotic sx of schizophrenia?

A

delusions, hallucinations, incoherence, catatonic or hyperactive behavior, flat affect

20
Q

What are key features for schizophrenia Dx?

A

Chronic illness (>6 mos), Deterioration from previous fxn level, complex psychotic symptoms

21
Q

What should be included in a DDx of schizophrenia?

A

Other psychotic disorders, substance use disorder, general medical disorder

22
Q

What are other psychotic disorders to include on a DDx of schizophrenia?

A

Schizophreniform disorder (

23
Q

What are general medical disorders to include in a DDx of schizophrenia?

A

Metabolic and hepatic diseases, Endocrine (hypo/per thyroid), infection (neurosyphillus), Neurologic (tumor, MS), DA agonists, Heavy metal poisoning

24
Q

What are key recent history findings for schizophrenia

A

Cognitive problems, behavior problems, Positive Sx, social isolation, unable to manage complex challenges

25
Q

What are labs you can do for schizophrenia?

A

CT/MRI of head, STD screening, CBC, urine drug screen, plasma drug levels, B12 levels, Thyroids functions

26
Q

What is acute management for schizophrenia?

A

Psychiatric care, psychotherapy, outreach and case management in community, medication

27
Q

What are the antipsychotic medications for schizophrenia?

A

D2 blockers (FGA: Chlorpromazine, haloperidol, thioridazine, trifluoperazine) (SGA: Clozapine, Risperidone, Paliperidone)

28
Q

What types of Sx of schizophrenia are D2 blockers effective at treating?

A

Positive symptoms

29
Q

What are side effects of first gen antipsychotics?

A

Acute Parkinson-like symptoms, movement disorders (tardive dyskinesia, tardive dystonia), sedation, CV, GI, sexual side effects, urinary retention, weight gain

30
Q

What is the advantage of using second gen antipsychotics?

A

No Parkinson Sx or TD

31
Q

What can clozapine cause?

A

agranulocytosis

32
Q

Why are second gen antipsychotics more effective?

A

D2 blockade plus 5HT2 blockade

33
Q

What are adverse effects of second gen antipsychotics?

A

weight gain, diabetes, premature death, stroke and pneumonia in elderly

34
Q

T/F: Metabolic syndrome is a major concern with antipsychotic meds?

A

True; monitor fasting glucose, lipids, BP, waist/BMI

35
Q

When is onset of schizophrenia?

A

early adulthood after years of vague “prodromal” symptoms

36
Q

what are key Sx of schizophrenia?

A

Cognitive impairment, affective Sx, perceptual & thought disturbance, social fxn impairment

37
Q

Are more males or females affected by schizophrenai?

A

Males > females (1.4:1)

Sobe (12 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions