5.5: Inherited Renal Disorders

Question 1

What are the two modes of inheritance in poylcystic disease?

Which is most common?

Answer 1

Autosomal Recessive

Autosomal Dominant (Most Common)

Question 2

Describe autosomal dominant polcystic disease?

Answer 2

Most frequent life-threatening heriditary disease

Important cause of End Stage Renal Disease

(Approx. 8-10% of those with ADPKD have ESRD)