autoimmune diseases Flashcards

1
Q

anti-ACh receptor

A

myasthenia gravis

tired at END of day

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2
Q

anti-BM

A

Goodpasture’s

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3
Q

anticardiolipin, lupus anticoag

A

SLE, antiphospholipid sx

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4
Q

Anticentromere

A

limited scleroderma (CREST sx)

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5
Q

anti-desmoglein (anti-desmosome)

A

pemphigus vulgaris

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6
Q

anti-dsDNA, anti-Smith (specific)

Anti-ANA (nonspecific)

A

SLE (lupus)

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7
Q

anti-glutamic acid decarboxylase (GAD-65)

A

DM I

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8
Q

antihemidesmosome

A

bullous pemphigoid

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9
Q

anti-histone

A

drug-induced lupus

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10
Q

anti-Jo-1, anti-SRP, anti-Mi-2

A

polymyositis, dermatomyositis

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11
Q

antimicrosomal, anti thyroglobulin

A

hashimoto’s thyroid

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12
Q

antimitochondrial

A

primary biliary cirrhosis

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13
Q

antiparietal

A

pernicious anemia

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14
Q

antiphospholipase A2 receptor

A

primary membranous nepropathy

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15
Q

anti-Scl-70 (anti-DNA topoisomerase I)

A

scleroderma

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16
Q

ASM ab

A

autoimmune hepatitis I

17
Q

antiSSA, anti SSB (antiRo, antiLa0

A

Sjogren sx

18
Q

anti-TSH receptor

A

graves disease

19
Q

anto-U1 RNP (ribonucleoprotein)

A

mixed CT disorder

20
Q

voltage gated Ca channel ab

A

Lambert-Eaton Sx

21
Q

IgA anti-endomysial, IgA anti-tissue transglutaminase

A

Celiac

22
Q

MPO-ANCA/p-ANCA

A

microscopic polyangiitis

eosinophilic granulomatosis with polyangiitis (CHURG-STRAUSS)

23
Q

PR3-ANCA/c-ANCA

A

granulomatosis with polyangiitis (WEGENER)

24
Q
Rheumatoid Factor (IgM ab that targets IgG Fc)
anti-CCP (specific)
A

Rheumatoid arthritis