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Pharm block IV > Supplements/Herbs > Flashcards

Supplements/Herbs Flashcards

1
Q

Vit A

toxicity

A

1st trimester birth defects
INC risk CVD/Osteoporisis
INC risk for lung cancer in smokers

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2
Q

Vit D

supplementation

A 
older adults
limited sunlight
dark skinned
obese
GI dz
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3
Q

Vit D

toxicity

A 
hypercalcemia
vascular tissue calcification
damage to heart, blood vessels, kidney
N/V
weight loss
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4
Q

Vit E

toxicity

A

bleeding with anticoagulants

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5
Q

Vit K

supplementation

A

all newborns given IM vit K at birth

-prevent hemorrhagic disease of newborn

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6
Q

Vit C

toxicity

A

GI issues

kidney stones

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7
Q 
Vit B1 (Thiamine) 
supplementation
A

chronic alcoholics
Wenicke-Korskoff Syndrome - fatal
(vision change, ataxia, memory loss)

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8
Q

Vit B12

supplementation

A 
elderly (poor absorption)
vegan, vegetarian 
alcoholics
pernicious anemia
GI malabsorption disorder
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9
Q

Folate

supplementation

A

women of childbearing age to prevent neural tube defects

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10
Q

melatonin

toxicity

A

not to be combined with anti-seizure meds or warfarin

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11
Q

bitter orange

A

nausea, constipation, weight loss

AE: especially with caffeine
INC heart rate/INC BP
stroke/MI

DI: MAOI (contains tyramine metabolites)
inhibits gut3A4

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12
Q

Ephedra

A

colds, fever, flu, weight loss

INC risk CVD/stroke, death

DI: additive effects with stimulants

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13
Q

Hawthorn

A

heart disease, CHF, High BP, angina

clinical trial - mild HF

DI: digoxin/nitrates, BP meds

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14
Q

Horse chESsnut

A

chronic venous insufficiency, varicose veins, hemorrhoids

clinical trial - YES

AE: raw see contains poisonous esculin toxin
may exacerbate kidney dz

DI: anticoagulants

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15
Q

Kava

A

insomnia, anxiety, depression, ADHD

clinical trial - YES

AE: liver damage, muscle spasms

DI: additive effects with sedatives
INC acetaminophen toxicity

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16
Q

St. John’s Wort

A

depression, anxiety, sleep dz, heart palpitation, wound healing, chronic fatigue, migraine

clinical trial - YES

AE: photosensitization
SEROTONIN SYNDROME (with SSRI, MAOI, TCA)
induce maine in bipolar, depressed, psychotic
potential birth defects

DI: antidepressant, INC expression 3A4/2C19
DEC oral contraceptives, statins, HIV PI

17
Q

Nutrient Claim

A

supplement address nutrient deficient

limited to those that have FDA established

18
Q

Health Claim

A

ability to reduce risk of dz or health condition

previously approved by FDA

19
Q

Structure - Function Claim

A

reflects how dietary supplement may affect or maintain normal body structures or functions

20
Q

product label contains

A

product has not been evaluated by FDA. not intended to dx, tx, cure or prevent any dz

21
Q

2007/2010 guidelines

A

companies inform FDA or serious AE

Manufactures responsible for meeting good manufacturing practices

22
Q

fish oil use

A

dec CVD, BP, HR, CHD death, sudden cardiac death

Pharm block IV (5 decks)

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