Haem toxicity Flashcards
1
Q
Aplastic anaemia (pancytopenia) Caused by:
A
Penicillamine
Gold
Carbamazepine
2
Q
Thrombocytopenia recovery usually 1-2 days after cessation of causative drug
A
T
3
Q
Haem malignancies are more common in alkylating agents than anti metabolites
A
T
4
Q
Drugs presenting greatest risk for agranulocytosis
A
Anti thyroid
Macrolides
Bactrim
Anticonvulsants
5
Q
Thrombocytopenia culprits
A
Quinidine Rifampin Sulfonamides Vanc Danozol
6
Q
Colchicine toxicity often initially presents with leukocytosis
A
T
Haem toxicity preceded also by GI and neuro signs and symptoms
Pancytopenia follows after 3-8/7
7
Q
Eosinophilia occurs in 5-40% patients receiving gold
A
T
8
Q
Mycophenolate mofetil affects neutrophils more commonly than lymphocytes
A
F
Other way around
9
Q
Dapsone induced agranulocytosis rare but 25-33 times more common in Leprosy patients
A
F
This is in DH PATIENTS
LEPROSY PT HAVE ALMOST NO risk
