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Kaplan Pharmacology > Antidepressants > Flashcards

Antidepressants Flashcards

1
Q

Phenelzine sulfate

A

MAO Inhibitors Antidepressants

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2
Q

Isocarboxazid

A

MAO Inhibitors Antidepressants

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3
Q

Tranylcypromine

A

MAO Inhibitors Antidepressants

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4
Q

Action of MAO Inhibitors Antidepressants

A

interferes with monoamine oxidase, allowing for increased concentration of neurotransmitters in synaptic space, causing stabilization of mood

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5
Q

Indications of MAO Inhibitors Antidepressants

A
  • depression

- chronic pain syndromes

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6
Q

Side effects of MAO Inhibitors Antidepressants

A

-HTN crisis when taken with foods containing tyramine (cheese, bologna, pepperoni, salami, figs, bananas, raisins, beer, red wine)

  • Photosensitivity
  • Weight gain
  • sexual dysfunction
  • orthostatic hypotension
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7
Q

Nursing considerations for MAO Inhibitors Antidepressants

A
  • not first line for depression
  • should not be takens with SSRIs
  • admin anti-HTN meds with caution
  • avoid other CNS depressants
  • no alcohol
  • d/c 10 days before general anesthesia
  • medications lower seizure threshold
  • monitor for urinary retention
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8
Q

Fluoxetine

A

SSRI Selective Reuptake inhibitors Antidepressant

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9
Q

Citalopram

A

SSRI Selective Reuptake inhibitors Antidepressant

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10
Q

Escitalopram

A

SSRI Selective Reuptake inhibitors Antidepressant

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11
Q

Fluvoxamine

A

SSRI Selective Reuptake inhibitors Antidepressant

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12
Q

Paroxetine

A

SSRI Selective Reuptake inhibitors Antidepressant

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13
Q

Sertraline

A

SSRI Selective Reuptake inhibitors Antidepressant

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14
Q

Venlafaxine

A

SNRI Selective Reuptake inhibitors Antidepressant

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15
Q

Duloxetine

A

SNRI Selective Reuptake inhibitors Antidepressant

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16
Q

Action of Selective Reuptake inhibitors Antidepressant

A

inhibits CNS neuronal uptake of serotonin

acts as stimulant counteracting depression and increasing motivation

17
Q

Indications of Selective Reuptake inhibitors Antidepressant

A
  • depression
  • OCD
  • obesity
  • bulimia
18
Q

Side effects of Selective Reuptake inhibitors Antidepressant

A
  • HA
  • dizziness
  • nervousness
  • insomnia
  • drowsiness
  • anxiety
  • tremor
  • dry mouth
  • GI upset
  • sweating
  • rash
  • URI
  • painful menstration
  • sexual dysfunction
  • weight gain
19
Q

Nursing considerations for Selective Reuptake inhibitors Antidepressant

A
  • take in AM
  • takes 4 wks to take effect
  • monitor weight
  • good mouth care
  • do not admin with MAOIs
  • monitor for thrombocytopenia
20
Q

Amitriptyline

A

Tricyclics Antidepressant

21
Q

Imipramin

A

Tricyclics Antidepressant

22
Q

action of Tricyclics Antidepressant

A

inhibits presynaptic reuptake of neurotransmitters norepinephrine and serotonin, anticholinergic action at CNS and peripheral receptors

23
Q

indications of Tricyclics Antidepressant

A
  • depression

- obstructive sleep apnea

24
Q

side effects of Tricyclics Antidepressant

A
  • sedation
  • anticholinergic
  • confusion
  • photosensitivity
  • disturbed concentration
  • orthostatic hypotension
  • bone marrow depression
  • urinary retention
25
Q

nursing considerations of Tricyclics Antidepressant

A
  • 1-3 wks for therapeutic effect, max response 6-9 weeks
  • daily dose at night to promote sleep and decrease day time side effects
  • orthostatic hypotension
  • side effects will decrease over time
  • sugarless lozenge for dry mouth
  • do not stop abruptly
  • avoid alcohol
  • avoid exposure to sun, wear sunscreen
  • OA: strong anticholinergic and sedation effects
26
Q

Bupropion

A

Heterocyclics Antidepressants

27
Q

Trazodone

A

Heterocyclics Antidepressants

28
Q

action of Heterocyclics Antidepressants

A

does not inhibit MAO, has some anticholinergic and sedative effects, alters effects of serotonin on CNS

29
Q

indications for Heterocyclics Antidepressants

A

tx of depression and smoking cessation

30
Q

side effects of Heterocyclics Antidepressants

A
  • dry mouth
  • nausea
  • bupropion - insomnia and agitation
  • trazodone - sedation, orthostatic hypotension
31
Q

nursing considerations of Heterocyclics Antidepressants

A
  • may require gradual reduction before stopping

- avoid alcohol, other CNS depressants for up to 1 week after end of therapy

Kaplan Pharmacology (26 decks)

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