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Flashcards in 510-6 Deck (32):
0

salivary amylase

digests starch

1

mucus

binds to food particles and aids in lubrication and swallowing

2

lingual lipase

activated by stomach acid once the food is swallowed and it digests fat

3

histatin

major component in wound repair

4

SLPI

antimicrobial agent important in HIV defense

5

IgA

antibody that neutralizes bacteria

6

lactoferrin

chelates iron so bacteria can't grow

7

Parasympathetic Stimulation of Salivary Glands

causes the production of serous, watery saliva

8

Sympathetic Stimulation of Salivary Glands

produces a small volume of thick mucus saliva

9

2 main types of salivary glands

minor- located throughout the oral cavity (except gingiva and hard palate)
major- three paired glands stimulated by nerves

10

mucoceles

blockage of minor mucus gland

11

3 major salivary glands

1.) parotid
2.) submandibular
3.) sublingual

12

Parotid

25% of total saliva volume
serous
located in temporal region of head
empties into STENSEN'S DUCT

13

Submandibular

70% of total saliva
mixed- mostly serous
empties into WHARTON'S DUCT next to the frenulum

14

Sublingual

5%
mixed- mostly mucus
empties into BARTHOLIN'S DUCT and DUCTS OF RIVINUS

15

Sialolith

salivary gland stone (most common in Wharton's Duct)

16

Sjogren's Syndrome

Autoimmune disorder where the body destroys its own salivary glands

17

pellicle

saliva that covers the tooth. important in bacteria defense.

18

plaque

when the pellicle gets colonized by bacteria

19

calculus

when the plaque calcifies

20

3 main bacterial colonizers of dental plaque

1.) s. sanguis
2.) s. mutanns
3.) a. viscosus

21

2 major types of salivary secretion

1.) serous
2.) mucus

22

acinus

cluster of cells arranged in a sphere around a hollow lumen

23

intercalated duct

joins acinus to striated duct. covered by myoepithelial cells. adds lysozymes and lactoferrin to saliva.

24

striated duct

adds bicarbonate to saliva and reabsorbs Na and Cl. striated pattern on tall cuboidal cells

25

serous demilune

during fixation the mucus cells swell leading to serous cells being pushed to the periphery of the acinus

26

myoepithelial cells

found on secretory acini and intercalated ducts. weakly contractile, similar to muscle cells but derived from epithelia

27

primary saliva

isotonic

28

secondary saliva

hyper tonic

29

Salivary protein secretion

NE binds to B andrenergic receptor which leads to a series of secondary messenger cascades (G protein, AC, cAMP) which eventually leads to the exocytosis of the proteins

30

Water and Electrolyte Salivary Secretion

Ach binds to muscarinic cholinergic receptor and NE binds to A andrenergic receptor which signals the intracellular release of calcium. this opens Na and Cl channels in the membrane and tight junctions. Aquaporins are also opened which leads to the movement of water.

31

Secretion of IgA

IgA produced by plasma cells. Epithelia cells produce secretory component that acts as a receptor and binds the IgA and by endocytosis brings it into the epithelial cell and releases it by exocytosis