L46-47 Eye Flashcards

1
Q

Word for removal of eye

A

Enucleation

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2
Q

What is the uveal tract?

A

vascular coat including choroid, ciliary body, iris

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3
Q

Word for nearsighted

A

Myopia

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4
Q

Word for farsighted

A

Hyperopia

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5
Q

Define Presbyopia

A

loss of accommodation with advancing age

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6
Q

Strabismus

A

crossed eyes Also called a squint

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7
Q

What is Proptosis?

A

Forward displacement of one eye

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8
Q

What can cause Proptosis or Exophthalmus?

A

Lacrimal gland lesions displace eye medially and down: sarcoid, neoplasms Optic nerve tumors displace directly forward: glioma, meningioma Grave’s disease Osteoma Orbital inflammatory conditions: cellulitis, Rhizopus or Mucor infection

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9
Q

What to think when see metastasis to the eye?

A

neuroblastoma (there are others also)

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10
Q

Blepharitis and Blepharoconjunctivitis

A

Inflammation of the eyelid skin for Blepharitis and involves the conjunctiva otherwise Due to any cause

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11
Q

Hordeolum

A

Acute purulent infection of gland/hair follicle Meibomian (internal) Zeis (external)

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12
Q

Chalazion

A

Painless nodule or papule of the eyelid Chronic inflammation of the meibomian glands These are resected because DDx of sebaceous carcinoma

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13
Q

What is a Wen?

A

Epidermal inclusion cyst Rupture leads to granuloma

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14
Q

Name for yellow plaque on nasal aspect of eyelids

A

Xanthelasma Made up of lipid containing macrophages Associated with aging, lipid disorders, biliary cirrhosis

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15
Q

Basal Cell carcinoma

A

Most common malignancy of the eye May invade the orbit, most commonly on lower lid or medial canthus

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16
Q

Sebaceous carcinoma

A

Second most common malignancy of the eyelid Two forms: 1) tumor/nodule formation like a chalazion, 2) Diffuse intra-epithelial Paget-like growth thickens eyelid, resembles blepharitis or ocular cicatrical pemphigoid Metastasizes first to parotid then to submandibular Mortality 1 in 5

17
Q

Syringoma

A

Benign skin appendage tumors, eccrine gland differentiation Familial is bilateral and diffuse, sporadic is singular or unilateral

18
Q

Why is the epithelium of conjunctiva special?

A

mucin-producing squamous epi

19
Q

What causes Trachoma?

A

Chlamydia trachomatis serotypes A, B, C

20
Q

What is Trachoma?

A

Causes Blindness in Asia, Africa, Middle East

Acute infectious fibrosing keratoconjunctivitis

Morphology: Trachomatous Pannus–membrane of blood vessels, lymphs w/necrotic germinal centers

Scarring opacifies cornea and distorts eyelids

21
Q

Trichiasis

A

Trachoma where eyelashes turn in due to cicatrix or tarsal plate

Follicular conjunctivitis seen when lid everted

22
Q

Pinguecula

A

Yellowish raised lesion of conjunctiva astride the nasal limbus of cornea but DOES NOT involve the cornea

Caused by actinic (solar) damage

Degeneration of elastin, collagen deposited

May cause corneal depression called Delle

23
Q

Pterygium

A

Wing-like proliferation of fibrovascular tissue extending from inner canthus ONTO the cornea (different from pinguecula)

Dissects in Bowman’s Layer onto cornea to impair vision and cause astigmatism, but does not cross midline so no blindness

In adults related to sun exposure

24
Q

Where are the stem cells for the cornea?

A

Limbus region that is at the margin of the cornea

This is where most conjunctival neoplasms start, but they don’t spread to the cornea

25
Q

3 types of squamous neoplasia in the conjunctiva

A

1) Squamous papilloma: benign, low risk HPV
2) Conjunctival intraepithelial neoplasia: CIN, UV light or high risk HPV 16, 18
3) Invasive squamous cell carcinoma: indolent, invasion shallow, rarely metastasizes

26
Q

Squamous papilloma of the conjunctiva

A

benign, low risk HPV

27
Q

Conjunctival intraepithelial neoplasia

A

CIN, UV light or high risk HPV 16, 18

28
Q

Invasive squamous cell carcinoma of the conjunctiva

A

indolent, invasion shallow, rarely metastasizes

29
Q

Malignant Melanomas of the conjunctiva

A

Pigmented nevi are common and no problem

Melanoma: generally unilateral, fair caucasions most risk, first have melanosis with atypia, spreads to parotid then submandibular, 25% mortality

30
Q

Causes of blue sclera

A

Osteogenesis imperfecta–collagen deficiency

Thinned: increased pressure from staphyloma or scleritis

Pigmented nevus beneath surface–nevus of Ota–too many melanocytes and then involves the eye

31
Q

What can happen to the sclera in RA?

A

Necrotizing scleritis from immune complexes

Also caused by vasculitis with Polyangiitis granulomatosis

32
Q

What is physically wrong with eye length for myopia and hyperopia?

A

Myopia: eye is too long

Hyperopia: eye is too short

33
Q

Layers of the cornea from outside to in

A

Epithelium

Basement membrane

Bowman’s layer (acellular)

Stroma

Descemet membrane (BM of endothelium)

Endothelium (neural crest origin)

34
Q

Descemet membrane lesions

A

Bullous keratopathy results from separation

Thickens with age

Site of Keiser-Fleischer ring; senile corneal arcus

35
Q

Hypopyon

A

Inflammatory cells in the anterior chamber of the eye

Can be exudate from the ciliary body, iris

36
Q

What causes this?

A

Herpetic infection leading to a dendritic ulcer

Can lead to scarring a loss of vision

Should never prescribe topical steroid unless you know they don’t have this and you are an ophthalmologist

37
Q
A