final

Question 1

hypersensitivity type? deposition of soluble IgG/antigen complexes

Answer 1

type III

Question 2

hypersensitivity type? cytotoxic T lymphocytes target hapten/carrier complexes

Answer 2

type IV

Question 3

hypersensitivity type? systemic anaphylaxis response due to massive release of histamine

Answer 3

type I

Question 4

hypersensitivity type?cytolysis of cells occurring after IgG-coated cell activates complement

Answer 4

type II

Question 5

hypersensitivity type? antigen stimulates IgE armed mast cells to release histamine in the tissue

Answer 5

type I

Question 6

which antibody class derived from colostrum is important in protecting the calves from septicemia?

Answer 6

IgG

Question 7

how much colostrum is needed for a calf?

Answer 7

2 L

Question 8

which vaccine would have the best chance of inducing immunity to individuals that are not vaccinated but live near vaccinated individuals?

Answer 8

modified live vaccine

Question 9

processing of non-replicating vaccine lead to what?

Answer 9

Th2 and antibody responses

Question 10

killed vaccines require what?

Answer 10

adjuvants

Question 11

what are the depot adjuvants?

Answer 11

• aluminum salts (Th2)

- water-in-oil (Th1)

Question 12

what are the particulate adjuvants?

Answer 12

• liposomes (endosomes processed in MHC II)

- carrier proteins links to CHO Ag (activating T-lymphocytess)

Question 13

the processing of MLVs leads to what?

Answer 13

Th1 response

Question 14

local administration of vaccines dictates what type of immune response?

Answer 14

mucosal immunity - IgA

systemic immunity - IgG

Question 15

systemic administration of vaccines dictates what type of immune response?

Answer 15

draining lymph nodes - IgG

Question 16

what is a type 1 vaccine?

Answer 16

• subunit vaccine

- stimulates Th2

Question 17

what is a type 2 vaccine

Answer 17

• gene deleted

- live replicating organisms contain gene deletions

Question 18

what is a type 3 vaccine?

Answer 18

• vectored vaccines
• replicating vectors
• heterologous genes

Question 19

what is type 4 vaccines?

Answer 19

• DNA vaccine

- naked DNA that is expressed into the protein of interest

Question 20

what type of immune hypersensitivity explains the leukocytoclastic vasculitis?

Answer 20

type III HS

Question 21

hidden antigen response

Answer 21

antigens in cells or tissues release antigens (from aged or damaged cells)

Question 22

molecular alterations of antigen examples

Answer 22

rheumatoid factor, develops after infection

Question 23

what is molecular mimicry?

Answer 23

antibody to pathogens cross-reacts with normal tissue antigens

Question 24

milk allergy in cattle is what type of HS?

Answer 24

type I

Question 25

type II HS autoimmune: AI mediated anemia:

Answer 25

autoantigen is erythrocyte epitopes

Question 26

type II HS autoimmune: AI mediated thrombocytopenia:

Answer 26

autoantigen is platelet epitopes

Question 27

type II HS autoimmune: myasthenia gravis:

Answer 27

anti-acetylcholine receptor antibodies

Question 28

type II HS autoimmune: graves disease:

Answer 28

anti-thyroid stimulating hormone receptor antibodies

-AI hyperthyroidism

Question 29

type II HS autoimmune: AI hypothyroidism:

Answer 29

antibodies to thyroid hormones and/or thryoglobulin

Question 30

type II HS autoimmune: pemphigus complex:

Answer 30

antibodies to desmosomes/basement membranes