HLA subtypes associated with diseases Flashcards

1
Q

A3

A

Hemochromatosis

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2
Q

B8

A
Addison disease (&DR3/4)
Myasthenia gravis
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3
Q

B27

A

Psoriatic arthritis
Ankylosing spondylitis
IBD-associated arthritis
Reactive arthritis (formerly Reiter syndrome)

  • PAIR
  • Also known as seronegative arthropathies
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4
Q

DQ2/DQ8

A

Celiac disease

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5
Q

DR2

A

Multiple sclerosis
hay fever
SLE
Goodpasture syndrome

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6
Q

DR3

A
Diabetes mellitus type 1 (&DR4)
SLE (&DR2)
Graves disease
Hashimoto thyroiditis (&DR5)
Addison disease (&DR4/B8)
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7
Q

DR4

A
Rheumatoid arthritis
diabetes mellitus type 1 (&DR3)
Addison disease (&DR3/B8)
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8
Q

DR5

A
Pernicious anemia-->vitamin B12 deficiency
Hashimoto thyroiditis (&DR3)
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