5.3 Damage & Repair

Question 1

Osteoporosis

Answer 1

• Ca deficit in blood triggers osteocytes to dissolve bone storage
• causes brittle weaker bones

Question 2

Steps of bone repair:

Answer 2

1. Hematoma formation (blood clot)
2. Fibrocartilaginous callous forms
3. Boney callus forms
4. Bone remodeling by osteocytes (resorption)

Question 3

Achondroplasia and gigantism

Answer 3

Both result with irregular closure of epiphyseal plates.

Question 4

Cleft palate

Answer 4

Failure of epiphyseal plate closure in soft or hard palate

Question 5

Spins bifida

Answer 5

Failure of epiphyseal plate in vertebral arches to close, subsequent neuro damage

Question 6

Scurvy is caused by

Answer 6

Vitamin C deficiency which causes lack of collagen production

Question 7

Vitamin C is critical for

Answer 7

The enzyme in Collagen production

Question 8

Rickets is caused by

Answer 8

Vitamin D, calcium or phosphate deficiency.

Results in calcium leaching from bones (more collagen too pliable bone)