Hepatic Pathology I, II, III Flashcards by Dillon Pryor | Brainscape

Q

Converts heme to biliverdin

A

Heme oxygenase

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Q

Converts biliverdin to bilirubin

A

Biliverdin reductase

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Q

UCB + glucuronic acid = CD

Enzyme for this reaction?

A

UDP-glucuronosyltransferase

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Q

Any bilirubin found in the urine is ___

A

Conjugated

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Q

Disease

Bile accumulation within the liver
Etiologies:
- Bile duct obstruction (intra or extrahepatic)
- Defect in bile secretion from hepatocytes

A

Cholestasis

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Q

Dx

Jaundice
Pruritis
Fat malabsorption
Elevated serum bilirubin (CB >50%)
Bilirubinuria
Absent urine urobilinogen
Increased serum alkaline phosphatase and GGT

A

Cholestasis

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Q

A

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