Physiology 2 - Physiological Processes of the Heart 1 Flashcards

1
Q

At -90mV (resting potential), which way does potassium flow - in or out of the cell?

A

Out

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2
Q

At -90mV, which way does sodium flow in or out of the cell?

A

In

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3
Q

What is meant by a functional syncytium?

A

Electrical coupling between all cells in the atria and (separately) all cells in the ventricles, allowing them to contact in synchrony

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4
Q

What is regarded as the intrinsic pacemaker?

A

SAN

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5
Q

Which nervous stimulations increase and decrease the rate of SAN depolarisation?

A

Sympathetic increases

Parasympathetic decreases

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6
Q

What is the result of the ventricular muscle fibre potential being held in positive figures for a while?

A

It is in a refractory state and therefore can’t fire again until it returns to resting membrane potential

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7
Q

What ions maintain this plateau of ventricular muscle contraction?

A

Ca2+

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8
Q

See page 4

A

See page 4!

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9
Q

When do funny channels open?

A

When the membrane potential decreases and becomes negative

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10
Q

Where does the electrical signal take the longest passing through?

A

AVN

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11
Q

Where are the 10 electrodes of the 12 lead ECG positioned?

A

6 on the chest

4 on the limbs - 1 is an earth

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12
Q

What do the limb leads measure?

A

The sum of electrical activity of the heart and the direction that electrical activity is moving in

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13
Q

What is the size of the electrical signals from the heart determined by?

A

Current

Direction of signal

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14
Q

Observed signal = …

A

E x cos(theta)

E = electrical event & theta = angle between event and ECG lead

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15
Q

Which nerve parasympathetically stimulates the SAN & AVN?

A

Vagus nerve

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16
Q

In an electrocardiogram (such as the one shown on the corresponding lecture), what does the P-R interval represent?

A

The time it takes for an electrical signal to pass from the SAN to the ventricles

17
Q

What does Q-T interval represent?

A

The time it takes a ventricular muscle fibre to depolarise and repolarise

18
Q

What is the resting potential of a ventricular muscle fibre membrane?

A

-90mV

19
Q

What is the predominant autonomic tone?

A

Parasympathetic