Lecture 3 Flashcards

1
Q

Dyspnea present?

A
  1. Severity
    • Oxygen dependent?
  2. Localization
    • Inspiratory vs. expiratory vs. restrictive
    • Upper airway, lower airway, parenchymal, thoracic wall, neurologic, abdominal (or not dyspnea…)
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2
Q

Cough mechanism

A

PROTECTIVE!!

  • works w/ mucociliary apparatus
  • both are less effective w/ disease!

NOTE: the trachea and large airways have the most “cough receptors”

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3
Q

Coughing

A

Coughing is a non-specific clinical sign ==> an accurate medical history is critical!
- acute vs chronic, static vs worsening, associations (ie. after exercise), productive vs. non-productive, other systemic signs

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4
Q

Potential coughing triggers

A
  1. owner is a smoker
  2. perfume/air fresheners
  3. dusty kitty litter
  4. house construction

Especially dig for some of these if patient has a cough history w/ no systemic disease or sign of infectious pneumonia

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5
Q

Coughing patient?

A

Consider any environmental exposure

  • boarding/grooming?
  • obtained from shelter?
  • outdoors? travel history?
  • walks? dog parks?
  • show? agility competitor?
  • heartworm prevention?
  • other sick/coughing animals at home?
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6
Q

Physical exam components of coughing patient

A
  1. Tracheal and cervical palpation
  2. Nasal discharge (nasal discharge w/ lots of drainage ==> drainage may irritate the trachea and cause cough)
  3. Changes in weight
  4. Skin lesions
  5. Cardiac abnormalities
  6. Lymphadenopathy
  7. Fundic examinations (ocular lesions may be seen w/ fungal and neoplastic disease)
  8. Rectal examination
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7
Q

Characteristics of a non-productive cough

A
  1. Usually loud, harsh, and paroxysmal
    - “Goose-honk”
  2. Most commonly associated with:
    • Upper airway disease (trachea and mainstem bronchi)
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8
Q

Productive cough

A
  1. Expectoration of sputum
    • Fluid/mucus/debris from the LOWER AIRWAYS (not much mucous/fluid is produced in upper airway)
  2. Most commonly associated with:
    • Lower airway disease
    • Pulmonary parenchymal disease

NOTE: productive cough yielding a foamy expectorant: foamy is associated w/ edema or heart failure
NOTE 2: Are they coughing and then just swallowing? Are they swallowing their “productive cough”???

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9
Q

Productive cough characteristics

A
  1. Typically softer in volume (“huff”)
  2. Less likely to be “paroxysmal”
  3. May be difficult to appreciate
    • Swallows sputum
    • Owner perceives as vomiting
      Terminal retch = NOT productive typically
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10
Q

Cats coughing?

A

Coughing in cats is RARE

  • When present should pursue aggressively!!
    1. Most common cause of coughing in cats is LOWER AIRWAY DISEASE (asthma)
      • Pleural space disease (rare)
      • Tracheal disease (uncommon)
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11
Q

Cardiogenic Cough

A
  1. Implies congestive heart failure… usually
    • Pulmonary edema

NOTE: Which abnormal breath sound should you be able to auscultate during your exam w/ cardiogenic cough?
- CRACKLES.

CHF: significant mitral valve disease ==> may lead to enlarged Left Atria ==> may compress mainstem bronchi ==> may see an upper airway non-productive cough (unless CHF is so severe there is pulmonary edema)

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12
Q

Cardiogenic Cough

A
  1. Cough classically worse at night
  2. Typically exhibit concurrent exercise intolerance at rest
  3. May have auscultation abnormality (ie. murmur)
  4. Perihilar edema on radiographs
    • Furosemide responsive
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13
Q

Non-cardiogenic cough

A
  1. Upper (large) airway
  2. Lower (small) airway
  3. Parenchymal
  4. Pleural Space
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14
Q

Upper Airway Cough: infectious

A

Infectious (tend to be honking, loud, non-productive)

  • Infectious tracheobronchitis
  • Parasitic (Oslerus osleri - filaroides) => K9 lungworm
  • Hilar lymph node enlargement (squishes carina; Fungal disease - especially histoplasmosis)

NOTE: upper airway coughs tend to be non-productive

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15
Q

Upper airway cough: non-infectious

A

Non-infectious

  • Tracheal collapse
  • Compressive masses (mural or extra-mural)
  • Foreign bodies
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16
Q

Lower Airway Cough

A
  1. Inflammatory airway disease
    • K9 chronic bronchitis
    • Feline lower airway disease
    • Eosinophilic bronchopneumopathy
  2. Smoke/chemical irritant inhalation
17
Q

Parenchymal Disease Cough: infectious

A

Infectious

  • Bacterial
  • Fungal disease (blastomyces, histoplasma, coccidioides)
  • Heartworm infection
  • Parasitic (Aleurostrongylus -cats, Filaroides hirthi -K9, Paragonimus -lung fluke)
  • Toxoplasma (more common in cats)
18
Q

Parenchymal disease cough: non-infectious

A

Noninfectious

  1. Neoplasia
    - Primary (caudal lung lobes)
    - Metastatic (multiple nodules)
  2. Lung lobe torsion (concurrent pleural effusion)
  3. Non-cardiogenic pulmonary edema (strangulation and electrocution are the top 2 causes)
19
Q

Diagnostic Plan: 1st tier tests

A

Common “first tier” tests

  1. CBC (look for inflammatory change)
  2. Thoracic radiographs (if stridor, stertor, goose-honk we’re thinking possible extra-thoracic so may want cervical rads)
  3. Fecal exam (float, sediment, Baermann)
  4. Heartworm testing
  5. Cytology (skin lesions, nasal discharge, lymph nodes)
20
Q

Diagnostic Plan: 2nd tier tests

A

Second tier testing

  1. cardiac evaluation
  2. chem panel (helps if there’s systemic disease - like fungal - may have infiltrated liver and increased enzymes)
  3. Urinalysis (fungal antigen titers)
  4. AIRWAY SAMPLING (TTW, ETW, BAL)
  5. Advanced imaging (fluoroscopy, CT)
  6. Lung aspirate/biopsy
  7. Bronchoscopy/thoracotomy
21
Q

Transtracheal and endotracheal wash

A
  1. When there is diffuse disease! (ie. bronchitis)
  2. instill 0.5-1.0 ml/kg per aliquot (repeat 2-3 times)
  3. catheter usually goes to the level of the carina (may go deeper w/ ETW)
  4. Recovered saline wash sample submitted for cytology and culture

NOTE: patient must be able to cough ==> consider when choosing anesthetic/sedative drugs

22
Q

Bronchoalveolar Lavage (BAL)

A

BAL:

  • LOCALIZED disease
    1. At least to 1 hemi-thorax (ie. right-sided aspiration pneumonia)
    2. Sample taken via guidance of bronchoscope - scope lodged in lower airway
    3. can take localized samples and can get greater volume yields
    4. patient may be oxygen-dependent until the patient coughs the saline up
23
Q

Empiric antibiotic therapy possible?

A
  1. Limited to 1 course (failure = airway sampling necessary)
  2. Discontinue 1-2 weeks before sampling airways, if possible
  3. Informed client consent (may complicate future diagnosis/tx if unsuccessful)
24
Q

Antitussives

A
  1. Opioids
    - Butorphanol (torbugesic)
    - Hydrocodone (combined w/ anticholinergic)
    - Loperamide (Imodium)
    - Diphenoxylate (also combined w/ anticholinergic)
  2. Opioid derivative
    - Dextromethorphan (OTC)

SIDE EFFECTS expected: sedation, constipation

25
Q

Points to Ponder!

A
  1. Cough is a PROTECTIVE MECHANISM
    - am I treating the patient or the owner? Is the cough interfering w/ quality of life in a big way?
    - what are my top differentials?
    • Collapsing trachea? Bronchitis?

Relative CONTRAINDICATIONS:

  • Productive cough
  • Infectious disease present