Antidotes/Treatments Flashcards

1
Q

Acetaminophen

A

N-acetylcysteine (replenishes glutathione)

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2
Q

Salicylates

A

NaHCO3 (alkalinize urine)

Dialysis

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3
Q

Amphetamines (basic)

A

NH4Cl (acidify urine)

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4
Q

Acetylcholinesterase inhibitors (organophosphates)

A

Atropine, Pralidoxime

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5
Q

Antimuscarinic, Anticholinergic agents

A

Physostigmine salicylate, control hyperthermia

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6
Q

β-blockers

A

Glucagon

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7
Q

Digitalis

A

Normalize K+, Lidocaine, Anti-dig Fab, fragments, Mg(2+)

“KLAM”

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8
Q

Iron

A

deFEroxamine, deFErasirox

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9
Q

Lead

A

CaEDTA, Dimercaprol, Succimer, Penicillamine

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10
Q

Mercury

A

Dimercaprol (BAL), Succimer

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11
Q

Arsenic

A

Dimercaprol (BAL), Succimer, Penicillamine

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12
Q

Gold

A

Dimercaprol (BAL), Succimer, Penicillamine

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13
Q

Copper

A

Penicillamine

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14
Q

Cyanide

A

Nitrite + Thiosulfate, Hydroxocobalamin

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15
Q

Methemoglobin

A

Methylene blue, vitamin C

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16
Q

Methanol, ethylene glycol (antifreeze)

A

Fomepizole > ethanol, dialysis

17
Q

Opioids

A

Naloxone/naltrexone

18
Q

Benzodiazepines

A

Flumazenil

19
Q

TCAs

A

NaHCO3 (plasma alkalinization)

20
Q

Heparin

A

Protamine

21
Q

Warfarin

A

Vitamin K, fresh frozen plasma

22
Q

tPA

A

Aminocaproic acid

23
Q

Streptokinase

A

Aminocaproic acid

24
Q

Urokinase

A

Aminocaproic acid

25
Q

Theophylline

A

β-blocker

26
Q

Rat poison (Brodifacoum)

A

Fresh Frozen Plasma