HIV Vaccine Flashcards

1
Q

Why is the cell an ideal environment for a virus?

A

The cell has ample energy and proteins.

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2
Q

When in evolution did the definition of self and non self become crucial?

A

With the evolution of the cell membrane.

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3
Q

What crucial events in the origin of AIDS happened in 1980?

A

There was an increase of unusual and opportunistic infections as well as rare cancers.

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4
Q

What rare disease was a hallmark of an aids pandemic?

A

Cryptococcus fungi infection (brain fungi).

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5
Q

What rare cancer was a hallmark of an aids pandemic?

A

Kaposi sarcoma.

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6
Q

What can also be a hallmark of an AIDS pandemic in addition to rare disease?

A

Increase in other diseases caused by unprotective sex on the rise, showing that safe sex practices are not being followed.

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7
Q

Who reported the increase in rare diseases at the start of the AIDS pandemic?

A

Ken Horne

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8
Q

Cryptococcus fungi was shown to rise at the start of the AIDS pandemic. What social group is this disease often see in?

A

Immunosupressed patients.

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9
Q

What happened in 1981 in regards to the AIDS pandemic?

A

The first mention of the affliction affecting gay men in NYC. This was dismissed by the City Health Officials.

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10
Q

What disease had 5 reported cases in LA at the time of the AIDS pandemic?

A

Pneumocystis pneumonia.

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11
Q

What happened in 1983 in regards to the AIDS pandemic?

A

Montagnier and Sineussi isolated a reterovirus from the lymph system of a patient.

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12
Q

What could the reterovirus isolated by Montagnier and Sineussi do?

A

Activate and kill T lymphocytes.

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13
Q

What two social groups was the same reterovirus, previously isolated from Montagnier and Sineussi , also isolated from?

A

Further gay paitents and haemophiliacs.

Haemophiliacs had the reterovirus as often intravenous drug users.

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14
Q

Who did the health secretary Margaret Heckler announce discovered the cause of AIDS in 1984?

A

Robert Gallo.

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15
Q

What type of reterovirus was the aids reterovirus known as?

A

A lentivirus- reterovirus with a long incubation period.

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16
Q

What does the AIDS reterovirus integrate into the genome as?

A

Provirus.

17
Q

In 1986 how many people were infected from AIDS?

A

1 million.

18
Q

Why could a drug be maid against AIDS?

A

It was known how a RT replicated.

19
Q

What was developed in 1987?

A

AZT.

20
Q

What was developed in 1992?

A

Combination therapies.

21
Q

What was developed in 1995 which meant the death rate of HIV dramatically fell?

A

Protease inhibitors.