EB24 Flashcards
Where are Mozabite, Maasai and Yemeni
Yemeni - middle east
Maasai - ss Africa
Mozabite - North Africa
what is the out of africa theory
bottle neck of people outside of Africa
populations outside of Africa are more closely related than populations within.
What is the gene flow between Mozabite, Maasai adn Yemeni
two non SS africa populations have some ss african ancestry: **linked to arabian slave trade 650-1600AD
- Mozabite: 26%
- – Yemeni 7%
ME ancestry in maasasi = 27% likely due to back migration from ME into Africa 20,000 years ago
what do we expect to happen if a ME or North African derived allele is introduced into the Massai and favoured by selection
increase in frequency by natural selection
what do we expect if the SS african allele is advantageous in the ME and north african and there is gene flow
increase in frequency in north africa annd me by natural selection
what would we expect if the local variants are better adapted in each case
then genes moving via gene flow will not be selectedf or
What are the two proxy parent popualtions (without admixture)
yoruba - african population almost 100% ancestry from WA
Druze = ME no evidence of arabian slave trade ancestry in
what does locus specific branch length tell us
measure of population differentiation
longer branch = more differences
what could we expect from the tree if tbhere is no admixture
ME popualtions to be more similar than African
what can we expect if admixture is occuring in the tree w/wo selection
gene flow from africa to yemeni so yemeni more like africa relative to druze
what would we expect if there is admixture with selection for african alleles
yemeni appear closer to yoruba than druze
what can tree patterns be used to show
look for NS and more specifically for selection since admixture
given an example of SS African alleles selected for
DPP6
give an example of ME
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